Literature DB >> 15974619

Pseudopyronines A and B, alpha-pyrones produced by a marine Pseudomonas sp. F92S91, and evidence for the conversion of 4-hydroxy-alpha-pyrone to 3-furanone.

Fangming Kong1, Maya P Singh, Guy T Carter.   

Abstract

In our search for inhibitors of bacterial fatty acid biosynthesis, two new alpha-pyrones, pseudopyronines A (1) and B (2), were isolated from a marine Pseudomonas sp. F92S91. The naturally occurring alpha-pyrones appeared to be unstable, evidenced by the conversion of pseudopyronine B into an oxidation product, 3-furanone (3). Structural elucidations were made by spectroscopic analyses including 2D-NMR data.

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Year:  2005        PMID： 15974619     DOI： 10.1021/np050038v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Pseudopyronine B, an inhibitor of sterol O-acyltransferase, produced by Pseudomonas sp. BYK11209.

Authors:  Aika Suzuki; Takashi Fukuda; Keisuke Kobayashi; Taichi Ohshiro; Hiroshi Tomoda
Journal:  J Antibiot (Tokyo)       Date:  2016-05-11       Impact factor: 2.649

2.  Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.

Authors:  Don D Nguyen; Alexey V Melnik; Nobuhiro Koyama; Xiaowen Lu; Michelle Schorn; Jinshu Fang; Kristen Aguinaldo; Tommie L Lincecum; Maarten G K Ghequire; Victor J Carrion; Tina L Cheng; Brendan M Duggan; Jacob G Malone; Tim H Mauchline; Laura M Sanchez; A Marm Kilpatrick; Jos M Raaijmakers; René De Mot; Bradley S Moore; Marnix H Medema; Pieter C Dorrestein
Journal:  Nat Microbiol       Date:  2016-10-31       Impact factor: 17.745

3.  Pyrones as bacterial signaling molecules.

Authors:  Alexander O Brachmann; Sophie Brameyer; Darko Kresovic; Ivana Hitkova; Yannick Kopp; Christian Manske; Karin Schubert; Helge B Bode; Ralf Heermann
Journal:  Nat Chem Biol       Date:  2013-07-14       Impact factor: 15.040

4.  A novel and widespread class of ketosynthase is responsible for the head-to-head condensation of two acyl moieties in bacterial pyrone biosynthesis.

Authors:  Darko Kresovic; Florence Schempp; Zakaria Cheikh-Ali; Helge B Bode
Journal:  Beilstein J Org Chem       Date:  2015-08-12       Impact factor: 2.883

5.  Identification and isolation of insecticidal oxazoles from Pseudomonas spp.

Authors:  Florian Grundmann; Veronika Dill; Andrea Dowling; Aunchalee Thanwisai; Edna Bode; Narisara Chantratita; Richard Ffrench-Constant; Helge B Bode
Journal:  Beilstein J Org Chem       Date:  2012-05-18       Impact factor: 2.883

6.  Pseudopyronine B: A Potent Antimicrobial and Anticancer Molecule Isolated from a Pseudomonas mosselii.

Authors:  S Nishanth Kumar; S R Aravind; Jubi Jacob; Geethu Gopinath; Ravi S Lankalapalli; T T Sreelekha; B S Dileep Kumar
Journal:  Front Microbiol       Date:  2016-08-26       Impact factor: 5.640
  6 in total

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