| Literature DB >> 15974612 |
Chih-Hua Chao1, Long-Fei Huang, Yi-Lea Yang, Jui-Hsin Su, Guey-Horng Wang, Michael Y Chiang, Yang-Chang Wu, Chang-Feng Dai, Jyh-Horng Sheu.
Abstract
Eleven new hippuristanols (1-4, 7-9, and 11-14), along with eight known metabolites (5, 6, 10, and 15-19), have been isolated from the gorgonian coral Isis hippuris. Single-crystal X-ray diffraction analyses supported the structure elucidation of known steroids 5 and 10. The absolute structures of hippuristanols were established by application of modified Mosher's method on 19. Compounds 14-19 have been found to exhibit significant cytotoxicity against several cancer cell lines.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15974612 DOI： 10.1021/np050033y
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050