Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I.

Literature DB >> 1597430

Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I.

Abstract

A polA12 recA718 double mutant of Escherichia coli, in which DNA polymerase I is temperature sensitive, was unable to maintain normal DNA synthesis or to form colonies on rich media at 42 degrees C. Overproduction of DnaE protein, the polymerizing alpha subunit of DNA polymerase III, restored bacterial DNA replication and cell viability, as well as the PolI-dependent replication of the plasmid carrying dnaE.

Entities: Gene Species

Mesh：

Substances：

Year: 1992 PMID： 1597430 PMCID： PMC206129 DOI： 10.1128/jb.174.12.4166-4168.1992

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

15 in total

1. Conditional lethality of the recA441 and recA730 mutants of Escherichia coli deficient in DNA polymerase I.

Authors: I Fijalkowska; P Jonczyk; Z Ciesla
Journal: Mutat Res Date: 1989-03 Impact factor: 2.433

Review 2. Mutation induced by DNA damage: a many protein affair.

Authors: H Echols; M F Goodman
Journal: Mutat Res Date: 1990 Sep-Nov Impact factor: 2.433

Review 3. Structure and replication of the colicin E1 plasmid.

Authors: W L Staudenbauer
Journal: Curr Top Microbiol Immunol Date: 1978 Impact factor: 4.291

4. DNA polymerase I: essential replication enzyme.

Authors: I R Lehman; D G Uyemura
Journal: Science Date: 1976-09-10 Impact factor: 47.728

5. Method for determining whether a gene of Escherichia coli is essential: application to the polA gene.

Authors: C M Joyce; N D Grindley
Journal: J Bacteriol Date: 1984-05 Impact factor: 3.490

6. Constitutive expression of SOS functions and modulation of mutagenesis resulting from resolution of genetic instability at or near the recA locus of Escherichia coli.

Authors: E M Witkin; J O McCall; M R Volkert; I E Wermundsen
Journal: Mol Gen Genet Date: 1982

7. Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli.

Authors: E M Witkin; V Roegner-Maniscalco; J B Sweasy; J O McCall
Journal: Proc Natl Acad Sci U S A Date: 1987-10 Impact factor: 11.205

8. Constitutive expression of the SOS response in recA718 mutants of Escherichia coli requires amplification of RecA718 protein.

Authors: J O McCall; E M Witkin; T Kogoma; V Roegner-Maniscalco
Journal: J Bacteriol Date: 1987-02 Impact factor: 3.490

9. Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli.

Authors: J B Sweasy; L A Loeb
Journal: J Biol Chem Date: 1992-01-25 Impact factor: 5.157

10. Variable expression of the ssb--1 allele in different strains of Escherichia coli K12 and B: differential suppression of its effects on DNA replication, DNA repair and ultraviolet mutagenesis.

Authors: H B Lieberman; E M Witkin
Journal: Mol Gen Genet Date: 1981

18 in total

Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I.

1. Conditional lethality of the recA441 and recA730 mutants of Escherichia coli deficient in DNA polymerase I.

Review 2. Mutation induced by DNA damage: a many protein affair.

Review 3. Structure and replication of the colicin E1 plasmid.

4. DNA polymerase I: essential replication enzyme.

5. Method for determining whether a gene of Escherichia coli is essential: application to the polA gene.

6. Constitutive expression of SOS functions and modulation of mutagenesis resulting from resolution of genetic instability at or near the recA locus of Escherichia coli.

7. Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli.

8. Constitutive expression of the SOS response in recA718 mutants of Escherichia coli requires amplification of RecA718 protein.

9. Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli.

10. Variable expression of the ssb--1 allele in different strains of Escherichia coli K12 and B: differential suppression of its effects on DNA replication, DNA repair and ultraviolet mutagenesis.

Review 1. Historical overview: searching for replication help in all of the rec places.

2. Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli.

3. The Escherichia coli dnaN159 mutant displays altered DNA polymerase usage and chronic SOS induction.

4. SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway.

5. Optimization of DNA polymerase mutation rates during bacterial evolution.

Review 6. Linkage map of Escherichia coli K-12, edition 10: the traditional map.

7. A genetic system to identify DNA polymerase beta mutator mutants.

8. Escherichia coli genes and pathways involved in surviving extreme exposure to ionizing radiation.

9. DNA strand transfer catalyzed by the 5'-3' exonuclease domain of Escherichia coli DNA polymerase I.

10. DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli.