Literature DB >> 15973551

[Generalized purpura as dermatologic manifestation of thrombcytopenia].

C Schulz1, R Kaufmann, F Ochsendorf.   

Abstract

A 72-year old patient was initially misdiagnosed with allergic vasculitis. He rapidly developed petechiae and mucosal bleeding. There were no other abnormal physical findings and the patient was otherwise in good physical condition. There was no history of trauma or infectious disease. The patient's complete blood count showed a marked thrombocytopenia of 2000/nl. A bone marrow biopsy confirmed the initial diagnosis of idiopathic thrombocytopenic purpura (ITP). The number of thrombocytes increased and the skin lesions resolved shortly after the patient was put on oral prednisone. This case emphasizes the importance of dermatologic symptoms in diagnosing severe systemic disease.

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Year:  2006        PMID: 15973551     DOI: 10.1007/s00105-005-0978-6

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  5 in total

Review 1.  Immune thrombocytopenic purpura.

Authors:  Douglas B Cines; Victor S Blanchette
Journal:  N Engl J Med       Date:  2002-03-28       Impact factor: 91.245

Review 2.  Treatment of refractory idiopathic thrombocytopenic purpura in adults.

Authors:  A Manoharan
Journal:  Br J Haematol       Date:  1991-10       Impact factor: 6.998

Review 3.  Initial management of adults with idiopathic (immune) thrombocytopenic purpura.

Authors:  J N George
Journal:  Blood Rev       Date:  2002-03       Impact factor: 8.250

Review 4.  Therapy of chronic idiopathic thrombocytopenic purpura in adults.

Authors:  P Berchtold; R McMillan
Journal:  Blood       Date:  1989-11-15       Impact factor: 22.113

5.  Platelet-associated and plasma anti-glycoprotein autoantibodies in chronic ITP.

Authors:  R McMillan; P Tani; F Millard; P Berchtold; L Renshaw; V L Woods
Journal:  Blood       Date:  1987-10       Impact factor: 22.113

  5 in total

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