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Literature DB >> 15972533

Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis.

Viswanath P Kurup¹, Raghavan Raju, Pachiappan Manickam.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed enhanced expression and represent chemokine, cytokine, growth factor, signal transduction, and transmembrane receptor genes as well as genes related to arginine metabolism.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2005 PMID： 15972533 PMCID： PMC1168612 DOI： 10.1128/IAI.73.7.4381-4384.2005

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

16 in total

1. Alkaline serine proteinase from Aspergillus fumigatus has synergistic effects on Asp-f-2-induced immune response in mice.

Authors: Viswanath P Kurup; Jin-Qi Xia; Horng-Der Shen; David A Rickaby; James D Henderson; Jordan N Fink; Hong Chou; Kevin J Kelly; Christopher A Dawson
Journal: Int Arch Allergy Immunol Date: 2002-10 Impact factor: 2.749

2. Purified recombinant A. fumigatus allergens induce different responses in mice.

Authors: V P Kurup; J Q Xia; R Crameri; D A Rickaby; H Y Choi; S Flückiger; K Blaser; C A Dawson; K J Kelly
Journal: Clin Immunol Date: 2001-03 Impact factor: 3.969

3. The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice.

Authors: Jane M Schuh; Kate Blease; Cory M Hogaboam
Journal: FASEB J Date: 2001-12-14 Impact factor: 5.191

4. Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.

Authors: J C MacPherson; S A Comhair; S C Erzurum; D F Klein; M F Lipscomb; M S Kavuru; M K Samoszuk; S L Hazen
Journal: J Immunol Date: 2001-05-01 Impact factor: 5.422

5. L-Arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis.

Authors: A P Gobert; S Daulouede; M Lepoivre; J L Boucher; B Bouteille; A Buguet; R Cespuglio; B Veyret; P Vincendeau
Journal: Infect Immun Date: 2000-08 Impact factor: 3.441

Review 6. Animal models of allergic bronchopulmonary aspergillosis.

Authors: Gabriele Grunig; Viswanath P Kurup
Journal: Front Biosci Date: 2003-01-01

7. Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

Authors: Kate Blease; Jane M Schuh; Claudia Jakubzick; Nicholas W Lukacs; Steven L Kunkel; Bharat H Joshi; Raj K Puri; Mark H Kaplan; Cory M Hogaboam
Journal: Am J Pathol Date: 2002-02 Impact factor: 4.307

8. Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung.

Authors: Eric S Silverman; Rebecca M Baron; Lyle J Palmer; Louis Le; Arlene Hallock; Venkat Subramaniam; Richard J Riese; Matthew D McKenna; Xuesong Gu; Towia A Libermann; Antonio Tugores; Kathleen J Haley; Stephanie Shore; Jeffrey M Drazen; Scott T Weiss
Journal: Am J Respir Cell Mol Biol Date: 2002-12 Impact factor: 6.914

9. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness.

Authors: Paul Van Eerdewegh; Randall D Little; Josée Dupuis; Richard G Del Mastro; Kathy Falls; Jason Simon; Dana Torrey; Sunil Pandit; Joyce McKenny; Karen Braunschweiger; Alison Walsh; Ziying Liu; Brooke Hayward; Colleen Folz; Susan P Manning; Alicia Bawa; Lisa Saracino; Michelle Thackston; Youssef Benchekroun; Neva Capparell; Mei Wang; Ron Adair; Yun Feng; JoAnn Dubois; Michael G FitzGerald; Hui Huang; René Gibson; Kristina M Allen; Alex Pedan; Melvyn R Danzig; Shelby P Umland; Robert W Egan; Francis M Cuss; Steuart Rorke; Joanne B Clough; John W Holloway; Stephen T Holgate; Tim P Keith
Journal: Nature Date: 2002-07-10 Impact factor: 49.962

Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis.

1. Alkaline serine proteinase from Aspergillus fumigatus has synergistic effects on Asp-f-2-induced immune response in mice.

2. Purified recombinant A. fumigatus allergens induce different responses in mice.

3. The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice.

4. Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.

5. L-Arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis.

Review 6. Animal models of allergic bronchopulmonary aspergillosis.

7. Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

8. Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung.

9. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness.

10. Co-induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide.

1. The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.

Review 2. Asthma and Fungus: Role in Allergic Bronchopulmonary Aspergillosis (ABPA) and Other Conditions.

3. Immune response modulation by curcumin in a latex allergy model.

Review 4. Initiation and Pathogenesis of Severe Asthma with Fungal Sensitization.