| Literature DB >> 15972250 |
J Psotová1, S Chlopcíková, P Miketová, V Simánek.
Abstract
The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml and the effect of PVEF correlated with the RA content. Dexrazoxan (DE), used as positive control, was less effective than PVEF or RA.Entities:
Mesh:
Substances:
Year: 2005 PMID: 15972250 DOI: 10.1016/j.fitote.2005.04.019
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882