OBJECTIVE: This study examined electrophysiological indices of preparation (readiness potential, RP) and execution (movement-associated potential, MAP) during automated and controlled reaction time (RT) in 13 chronic tic disorder, 17 habit disorder, and 14 control participants. BACKGROUND: Both tic and habit disorders are hypothesized to involve states of heightened activation, which could impede initiation and the control of complex motor actions. METHOD: The electrophysiological signal was recorded from 4 electrodes (Fz, C3, C4, Pz) during a fixed 4-second foreperiod reaction time task. RESULTS: During automated responses, controls showed a shorter RP peak onset, and during controlled responses a longer MAP peak onset, compared with both clinical groups. The controls were the only group who showed a consistent linear relationship between RP and RT. CONCLUSIONS: Patients with chronic tic as well as habit disorder may not modulate cortical activation optimally in planning and executing both automated and controlled responses.
OBJECTIVE: This study examined electrophysiological indices of preparation (readiness potential, RP) and execution (movement-associated potential, MAP) during automated and controlled reaction time (RT) in 13 chronic tic disorder, 17 habit disorder, and 14 control participants. BACKGROUND: Both tic and habit disorders are hypothesized to involve states of heightened activation, which could impede initiation and the control of complex motor actions. METHOD: The electrophysiological signal was recorded from 4 electrodes (Fz, C3, C4, Pz) during a fixed 4-second foreperiod reaction time task. RESULTS: During automated responses, controls showed a shorter RP peak onset, and during controlled responses a longer MAP peak onset, compared with both clinical groups. The controls were the only group who showed a consistent linear relationship between RP and RT. CONCLUSIONS:Patients with chronic tic as well as habit disorder may not modulate cortical activation optimally in planning and executing both automated and controlled responses.
Authors: B Biswal; J L Ulmer; R L Krippendorf; H H Harsch; D L Daniels; J S Hyde; V M Haughton Journal: AJNR Am J Neuroradiol Date: 1998-09 Impact factor: 3.825
Authors: R T Malison; C J McDougle; C H van Dyck; L Scahill; R M Baldwin; J P Seibyl; L H Price; J F Leckman; R B Innis Journal: Am J Psychiatry Date: 1995-09 Impact factor: 18.112
Authors: Simon Morand-Beaulieu; Kieron P O'Connor; Maxime Richard; Geneviève Sauvé; Julie B Leclerc; Pierre J Blanchet; Marc E Lavoie Journal: Front Psychiatry Date: 2016-05-10 Impact factor: 4.157