| Literature DB >> 15970504 |
Bagavathi S Perumal1, Kishore R Sakharkar, Vincent Tak Kwong Chow, Kangueane Pandjassarame, Meena Kishore Sakharkar.
Abstract
A compilation of intron positions obtained from a large number of eukaryotic genomes across orthologous tubulins is explored for molecular evolution. Comparison of intron positions for 41 alpha, 80 beta, and 30 gamma tubulin genomic sequences indicates that the putative ancestral tubulin gene contained at least 19, 33, and 52 intron positions distributed at different sites in the coding regions for alpha, beta, and gamma tubulins, respectively. Many intron positions are old and are conserved across different eukaryotic lineages and intron distribution patterns are consistent with 'introns-early' hypothesis.Mesh:
Substances:
Year: 2005 PMID: 15970504 DOI: 10.2741/1706
Source DB: PubMed Journal: Front Biosci ISSN: 1093-4715