| Literature DB >> 15970010 |
Gamze Sinem Caglar1, Byron Asimakopoulos, Nikos Nikolettos, Klaus Diedrich, Safaa Al-Hasani.
Abstract
The advent of recombinant gonadotrophins brought significant changes in fertility therapy. Treatment options with recombinant gonadotrophins add more to knowledge on folliculogenesis and ovarian steroidogenesis. Over a decade, recombinant LH (rLH) has been used for clinical trials, and the amount of peripheral LH that is necessary for optimal follicular growth, oocyte maturation, subsequent embryo development and assisted reproduction outcome during ovulation induction can now be better evaluated. This review evaluates the effect of rLH supplementation on ovarian stimulation and assisted reproduction outcome. The studies conducted with rLH supplementation in ovarian stimulation in different groups of patients and in cases of controlled ovarian stimulation are clearly discussed in this review.Entities:
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Year: 2005 PMID: 15970010 DOI: 10.1016/s1472-6483(10)61123-6
Source DB: PubMed Journal: Reprod Biomed Online ISSN: 1472-6483 Impact factor: 3.828