Literature DB >> 15969776

A drug dosage table is a useful tool to facilitate prescriptions of antiretroviral drugs for children in Thailand.

M Ponnet1, K Frederix, W Petdachai, D Wilson, A Eksaengsri, R Zachariah.   

Abstract

Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors. We describe (a) the formulation of a standardized drug dosage table to facilitate antiretroviral drug (ARV) prescriptions for children, (b) the acceptability of such a table among doctors and (c) the safety and efficacy of drug doses in the table. Acceptability was assessed using a questionnaire. Safety and efficacy were assessed on the basis of incidence of adverse effects and virological response to treatment, respectively. Of all doctors (n=18), 17 (94%) found that the table was practical to use, avoided miscalculations and made them more confident with prescriptions. Of 49 children prescribed ARVs, less than 5% had adverse side-effects. All ARV-naïve children achieved undetectable viral loads within six months of ART. In our setting, a standardized drug dosage table provided a simple and reliable tool that facilitated ARV prescriptions for children.

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Year:  2005        PMID: 15969776     DOI: 10.1258/0956462054094114

Source DB:  PubMed          Journal:  Int J STD AIDS        ISSN: 0956-4624            Impact factor:   1.359


  4 in total

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2.  Underdosing of antiretrovirals in UK and Irish children with HIV as an example of problems in prescribing medicines to children, 1997-2005: cohort study.

Authors:  Esse N Menson; A Sarah Walker; Mike Sharland; Carole Wells; Gareth Tudor-Williams; F Andrew I Riordan; E G Hermione Lyall; Diana M Gibb
Journal:  BMJ       Date:  2006-05-20

3.  Managing HIV-infected children in a low-resource, public clinic: a comparison of nurse vs. clinical officer practices in ART refill, calculation of adherence and subsequent appointments.

Authors:  Ralf Weigel; Caryl Feldacker; Hannock Tweya; Chimwemwe Gondwe; Jane Chiwoko; Joe Gumulira; Mike Kalulu; Sam Phiri
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Review 4.  Optimizing drugs to reach treatment targets for children and adolescents living with HIV.

Authors:  Martina Penazzato; Janice Lee; Edmund Capparelli; Shaffiq Essajee; Nathan Ford; Atieno Ojoo; Fernando Pascual; Nandita Sugandhi; Marc Lallemant
Journal:  J Int AIDS Soc       Date:  2015-12-02       Impact factor: 5.396

  4 in total

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