BACKGROUND: The published articles examining obesity and CABG surgery contain conflicting results about the role of body mass index (BMI) as a risk factor for in-hospital mortality. METHODS AND RESULTS: We studied 16 218 patients who underwent isolated CABG in the Providence Health System Cardiovascular Study Group database from 1997 to 2003. The effect of BMI on in-hospital mortality was assessed by logistic regression, with BMI group (underweight, normal, overweight, and 3 subgroups of obesity) as a categorical variable or transformations, including fractional polynomials, of BMI as a continuous variable. BMI was not a statistically significant risk factor for mortality in any of these assessments. However, using cumulative sum techniques, we found that the lowest risk-adjusted CABG in-hospital mortality was in the high-normal and that overweight BMI subgroup patients with lower or higher BMI had slightly increased mortality. CONCLUSIONS: Body size is not a significant risk factor for CABG mortality, but the lowest mortality is found in the high-normal and overweight subgroups compared with obese and underweight.
BACKGROUND: The published articles examining obesity and CABG surgery contain conflicting results about the role of body mass index (BMI) as a risk factor for in-hospital mortality. METHODS AND RESULTS: We studied 16 218 patients who underwent isolated CABG in the Providence Health System Cardiovascular Study Group database from 1997 to 2003. The effect of BMI on in-hospital mortality was assessed by logistic regression, with BMI group (underweight, normal, overweight, and 3 subgroups of obesity) as a categorical variable or transformations, including fractional polynomials, of BMI as a continuous variable. BMI was not a statistically significant risk factor for mortality in any of these assessments. However, using cumulative sum techniques, we found that the lowest risk-adjusted CABG in-hospital mortality was in the high-normal and that overweight BMI subgroup patients with lower or higher BMI had slightly increased mortality. CONCLUSIONS: Body size is not a significant risk factor for CABG mortality, but the lowest mortality is found in the high-normal and overweight subgroups compared with obese and underweight.
Authors: Marcovalerio Melis; Jill M Weber; James M McLoughlin; Erin M Siegel; Sarah Hoffe; Ravi Shridhar; Kiran K Turaga; George Dittrick; E Michelle Dean; Richard C Karl; Kenneth L Meredith Journal: Ann Surg Oncol Date: 2010-09-24 Impact factor: 5.344
Authors: Chuntao Wu; Fabian T Camacho; Andrew S Wechsler; Stephen Lahey; Alfred T Culliford; Desmond Jordan; Jeffrey P Gold; Robert S D Higgins; Craig R Smith; Edward L Hannan Journal: Circulation Date: 2012-04-30 Impact factor: 29.690
Authors: Marcovalerio Melis; Jill Weber; Ravi Shridhar; Sarah Hoffe; Khaldoun Almhanna; Richard C Karl; Kenneth L Meredith Journal: BMJ Open Date: 2013-05-02 Impact factor: 2.692
Authors: Robert M MacGregor; Ali J Khiabani; Nadia H Bakir; Meghan O Kelly; Samuel C Perez; Hersh S Maniar; Richard B Schuessler; Marc R Moon; Spencer J Melby; Ralph J Damiano Journal: Innovations (Phila) Date: 2021-06-27