Literature DB >> 15967654

MHC multimer technology: current status and future prospects.

Arnold H Bakker1, Ton N M Schumacher.   

Abstract

The detection of antigen-specific T cell responses by MHC multimer staining is rapidly becoming one of the core immunological techniques, and the technology to produce MHC multimers has been optimized substantially in recent years. Furthermore, recent work demonstrates the potential of high-throughput detection of T cell responses and suggests that manipulation of T cell responses through the use of multimeric MHC reagents is also feasible.

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Year:  2005        PMID: 15967654     DOI: 10.1016/j.coi.2005.06.008

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  25 in total

1.  Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers.

Authors:  Rikke Sick Andersen; Pia Kvistborg; Thomas Mørch Frøsig; Natasja W Pedersen; Rikke Lyngaa; Arnold H Bakker; Chengyi Jenny Shu; Per thor Straten; Ton N Schumacher; Sine Reker Hadrup
Journal:  Nat Protoc       Date:  2012-04-12       Impact factor: 13.491

2.  Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.

Authors:  Arnold H Bakker; Rieuwert Hoppes; Carsten Linnemann; Mireille Toebes; Boris Rodenko; Celia R Berkers; Sine Reker Hadrup; Wim J E van Esch; Mirjam H M Heemskerk; Huib Ovaa; Ton N M Schumacher
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-28       Impact factor: 11.205

3.  Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers.

Authors:  Gijsbert M Grotenbreg; Nadia R Roan; Eduardo Guillen; Rob Meijers; Jia-Huai Wang; George W Bell; Michael N Starnbach; Hidde L Ploegh
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-01       Impact factor: 11.205

4.  Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

Authors:  Sine Reker Hadrup; Arnold H Bakker; Chengyi J Shu; Rikke S Andersen; Jerre van Veluw; Pleun Hombrink; Emilie Castermans; Per Thor Straten; Christian Blank; John B Haanen; Mirjam H Heemskerk; Ton N Schumacher
Journal:  Nat Methods       Date:  2009-06-21       Impact factor: 28.547

5.  Soluble MHC-peptide complexes: tools for the monitoring of T cell responses in clinical trials and basic research.

Authors:  Philippe Guillaume; Danijel Dojcinovic; Immanuel F Luescher
Journal:  Cancer Immun       Date:  2009-09-25

Review 6.  Epitope prediction and identification- adaptive T cell responses in humans.

Authors:  John Sidney; Bjoern Peters; Alessandro Sette
Journal:  Semin Immunol       Date:  2020-10-31       Impact factor: 11.130

Review 7.  Human memory T cells: generation, compartmentalization and homeostasis.

Authors:  Donna L Farber; Naomi A Yudanin; Nicholas P Restifo
Journal:  Nat Rev Immunol       Date:  2013-12-13       Impact factor: 53.106

Review 8.  T-cell receptor affinity in the age of cancer immunotherapy.

Authors:  Michele M Hoffmann; Jill E Slansky
Journal:  Mol Carcinog       Date:  2020-05-09       Impact factor: 4.784

9.  Dextramer reagents are effective tools for quantifying CMV antigen-specific T cells from peripheral blood samples.

Authors:  Joseph D Tario; George L Chen; Theresa E Hahn; Dalin Pan; Rosemary L Furlage; Yali Zhang; Liselotte Brix; Charlotte Halgreen; Kivin Jacobsen; Philip L McCarthy; Paul K Wallace
Journal:  Cytometry B Clin Cytom       Date:  2014-10-23       Impact factor: 3.058

Review 10.  MHC-based detection of antigen-specific CD8+ T cell responses.

Authors:  Sine Reker Hadrup; Ton N Schumacher
Journal:  Cancer Immunol Immunother       Date:  2010-02-23       Impact factor: 6.968

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