Literature DB >> 15966243

Primary squamous cell carcinoma of the stomach: a case report with immunohistochemical and molecular biologic studies.

Junko Takita1, Hiroyuki Kato, Tatsuya Miyazaki, Masanobu Nakajima, Yasuyuki Fukai, Norihiro Masuda, Ryokuhei Manda, Minoru Fukuchi, Hiroyuki Kuwano.   

Abstract

Primary squamous cell carcinoma (SCC) of the stomach is an extremely rare tumor and its pathogenesis is still unknown. We report a case of SCC of the stomach in a 69-year-old man. The patient's stomach contained an area of SCC surrounded by squamous metaplasia. To our knowledge, this is the first reported study to have investigated the pathogenesis of this tumor type by immunohistochemistry, liquid hybridization assay for human papilloma virus (HPV) infection, and polymerase chain reaction for Epstein-Barr virus (EBV) infection. These tests yielded proof of EBV infection in surgical specimens of the tumor. Therefore, we suggest that EBV infection may be involved in the pathogenesis of SCC arising in the stomach.

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Year:  2005        PMID: 15966243

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  13 in total

1.  An unexpected mucosal metaplasia at the gastric cardia in longstanding pernicious anemia.

Authors:  Mohammad H Derakhshan; Andrew Crumley; Matthew Forshaw; David R Mitchell; James J Going
Journal:  Am J Gastroenterol       Date:  2015-10       Impact factor: 10.864

Review 2.  Primary squamous cell carcinoma of the stomach: a case report and literature review.

Authors:  Shengqiang Gao; Dongdong Chen; Lidong Huang; Ruijie Dai; Yunfeng Shan
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

Review 3.  Epstein-Barr virus-associated gastric adenosquamous carcinoma with concurrent gastric carcinoma with lymphoid stroma: a case report and review of the literature.

Authors:  Fang Cao; Yan Yan; Dongfeng Niu; Xiaozheng Huang; Ling Jia; Xinting Diao; Zhongwu Li
Journal:  BMC Gastroenterol       Date:  2022-07-16       Impact factor: 2.847

4.  Gastric squamous cell carcinoma and gastric adenosquamous carcinoma, clinical features and outcomes of rare clinical entities: a National Cancer Database (NCDB) analysis.

Authors:  Mehmet Akce; Renjian Jiang; Olatunji B Alese; Walid L Shaib; Christina Wu; Madhusmita Behera; Bassel F El-Rayes
Journal:  J Gastrointest Oncol       Date:  2019-02

5.  Exuberant squamous metaplasia of the gastric mucosa in a patient with gastric adenocarcinoma.

Authors:  Sangjeong Ahn; Go Eun Bae; Kyoung-Mee Kim
Journal:  Diagn Pathol       Date:  2015-04-30       Impact factor: 2.644

6.  Clinicopathological Characteristics, Treatment, and Prognosis of 21 Patients with Primary Gastric Squamous Cell Carcinoma.

Authors:  Yang Chen; Hong Zhu; Feng Xu; Yidan Cao; Xingting Gu; Yuming Wan; Hongfeng Gou
Journal:  Gastroenterol Res Pract       Date:  2016-07-05       Impact factor: 2.260

7.  Primary Squamous Cell Carcinoma of the Remnant Stomach after Subtotal Gastrectomy.

Authors:  Yeon Soo Chang; Min Sung Kim; Dong Hee Kim; Seulkee Park; Ji Young You; Joon Kil Han; Seong Hwan Kim; Ho Jung Lee
Journal:  J Gastric Cancer       Date:  2016-06-24       Impact factor: 3.720

8.  Squamous cell carcinoma arising from an unknown primary site metastasizing to the stomach: A case report.

Authors:  Guangyao Wang; Ping Chen; Lei Shi; Wei Zhao
Journal:  Oncol Lett       Date:  2014-01-28       Impact factor: 2.967

9.  Primary squamous cell carcinoma of the stomach: A case report.

Authors:  Sun Hwi Hwang; Jung Hee Lee; Kyungbin Kim; Dong Hun Shin; Jee Yeon Kim; Mee Young Sol; Kyung Un Choi
Journal:  Oncol Lett       Date:  2014-09-01       Impact factor: 2.967

10.  Primary Squamous Cell Carcinoma of Stomach: A Rare Entity - Case Report and Brief Review of Literature.

Authors:  Rashmi Patnayak; Venkatarami Reddy; Amitabh Jena
Journal:  J Surg Tech Case Rep       Date:  2015 Jul-Dec
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