| Literature DB >> 15965604 |
Andrey Bogoyavlenskiy1, Vladimir Berezin, Alexey Prilipov, Eugeniy Usachev, Olga Lyapina, Svetlana Levandovskaya, Ilya Korotetskiy, Valentina Tolmacheva, Nailya Makhmudova, Svetlana Khudyakova, Gulnur Tustikbaeva, Irina Zaitseva, Elmira Omirtaeva, Olga Ermakova, Klara Daulbaeva, Saule Asanova, Aydyn Kydyrmanov, Marat Sayatov, Daniel King.
Abstract
Newcastle disease virus (NDV) infects domesticated and wild birds throughout the world and has the possibility to cause outbreaks in chicken flocks in future. To assess the evolutionary characteristics of 10 NDV strains isolated from chickens in Kazakhstan during 1998 we investigated the phylogenetic relationships among these viruses and viruses described previously. For genotyping, fusion (F) gene phylogenetic analysis (nucleotide number 47-421) was performed using sequences of Kazakhstanian isolates as compared to sequences of selected NDV strains from GenBank. Phylogenetic analysis showed that all newly characterized strains belonged to the genetic group designated as VIIb. All strains possessed a virulent fusion cleavage site (RRQRR/F) belonging to velogenic or mesogenic pathotypes with intracerebral pathogenicity indexes (ICPI) varying from 1.05 to 1.87.Entities:
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Year: 2005 PMID: 15965604 DOI: 10.1007/s11262-004-2195-2
Source DB: PubMed Journal: Virus Genes ISSN: 0920-8569 Impact factor: 2.332