| Literature DB >> 1596515 |
R J Wanders1, S Denis, C W van Roermund, C Jakobs, H J ten Brink.
Abstract
We have investigated the activation of pristanic acid to its CoA-ester in rat liver. The results show that peroxisomes, mitochondria as well as microsomes contain pristanoyl-CoA synthetase activity. On the basis of competition experiments and immunoprecipitation studies using antibodies raised against rat liver microsomal long-chain fatty acyl-CoA synthetase (EC 6.2.1.3) we conclude that pristanic acid is activated by the same enzyme which activates long-chain fatty acids, i.e., long-chain fatty acyl-CoA synthetase.Entities:
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Year: 1992 PMID： 1596515 DOI： 10.1016/0005-2760(92)90056-2
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002