Literature DB >> 15964271

DNA repair: how to PIKK a partner.

Kevin Hiom1.   

Abstract

In eukaryotes, members of the phosphoinositide-3-kinase-related protein kinase (PIKK) family co-ordinate the cellular response to DNA damage. But how do these important kinases detect DNA damage and relay this information to the DNA repair and checkpoint machinery?

Mesh：

Substances：

Year:  2005        PMID： 15964271     DOI： 10.1016/j.cub.2005.06.012

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

1.  Cell context-dependent involvement of ATR in early stages of retroviral replication.

Authors:  Yi-Xin Yang; Vincent Guen; Jonathan Richard; Eric A Cohen; Lionel Berthoux
Journal:  Virology       Date:  2009-11-13       Impact factor: 3.616

2.  ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.

Authors:  Aifang Cheng; Teng Zhao; Kai-Hei Tse; Hei-Man Chow; Yong Cui; Liwen Jiang; Shengwang Du; Michael M T Loy; Karl Herrup
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-26       Impact factor: 11.205

3.  Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage.

Authors:  Andrea Huwiler; Nataliya Kotelevets; Cuiyan Xin; Oleksandr Pastukhov; Josef Pfeilschifter; Uwe Zangemeister-Wittke
Journal:  Br J Pharmacol       Date:  2011-01       Impact factor: 8.739

4.  ATM loss disrupts the autophagy-lysosomal pathway.

Authors:  Aifang Cheng; Kai-Hei Tse; Hei-Man Chow; Yunqiao Gan; Xuan Song; Fulin Ma; Yi Xuan Yvonne Qian; Weiyi She; Karl Herrup
Journal:  Autophagy       Date:  2020-08-14       Impact factor: 16.016
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.