Literature DB >> 15963767

Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification.

Eleonora Minina1, Sabine Schneider, Mark Rosowski, Roland Lauster, Andrea Vortkamp.   

Abstract

Disturbed fibroblast growth factor (Fgf) and transforming growth factor beta (Tgfbeta) signaling lead to a variety of human skeletal disorders. To reveal the possible function and interaction of these signaling systems we have started to analyze the expression patterns of signaling factors, antagonists, receptors and transducers of these pathways in forelimbs of mouse embryos and compared them to the expression of established markers including Ihh. In addition to defining their expression domains in the developing bone, our study identified new subpopulations of chondrocytes characterized by the expression of distinct combinations of markers.

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Year:  2005        PMID: 15963767     DOI: 10.1016/j.modgep.2005.04.012

Source DB:  PubMed          Journal:  Gene Expr Patterns        ISSN: 1567-133X            Impact factor:   1.224


  20 in total

1.  Fibrodysplasia ossificans progressiva: a human genetic disorder of extraskeletal bone formation, or--how does one tissue become another?

Authors:  Eileen M Shore
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2012 Jan-Feb       Impact factor: 5.814

2.  Wnt gene expression in the post-natal growth plate: regulation with chondrocyte differentiation.

Authors:  Anenisia C Andrade; Ola Nilsson; Kevin M Barnes; Jeffrey Baron
Journal:  Bone       Date:  2007-01-20       Impact factor: 4.398

3.  Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in hereditary multiple exostoses.

Authors:  Christina Mundy; Evan Yang; Hajime Takano; Paul C Billings; Maurizio Pacifici
Journal:  J Biol Chem       Date:  2018-04-05       Impact factor: 5.157

Review 4.  Transcriptional networks controlling chondrocyte proliferation and differentiation during endochondral ossification.

Authors:  Manuela Wuelling; Andrea Vortkamp
Journal:  Pediatr Nephrol       Date:  2009-12-01       Impact factor: 3.714

5.  Bone morphogenetic protein 2 stimulates endochondral ossification by regulating periosteal cell fate during bone repair.

Authors:  Yan Yiu Yu; Shirley Lieu; Chuanyong Lu; Céline Colnot
Journal:  Bone       Date:  2010-03-27       Impact factor: 4.398

Review 6.  A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation.

Authors:  Elena Kozhemyakina; Andrew B Lassar; Elazar Zelzer
Journal:  Development       Date:  2015-03-01       Impact factor: 6.868

Review 7.  TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.

Authors:  Elena Gallo MacFarlane; Julia Haupt; Harry C Dietz; Eileen M Shore
Journal:  Cold Spring Harb Perspect Biol       Date:  2017-11-01       Impact factor: 10.005

Review 8.  The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.

Authors:  Maurizio Pacifici
Journal:  Matrix Biol       Date:  2017-12-24       Impact factor: 11.583

9.  Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme.

Authors:  Carlos I Lorda-Diez; Juan A Montero; Carmen Martinez-Cue; Juan A Garcia-Porrero; Juan M Hurle
Journal:  J Biol Chem       Date:  2009-08-28       Impact factor: 5.157

10.  BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

Authors:  Kelsey N Retting; Buer Song; Byeong S Yoon; Karen M Lyons
Journal:  Development       Date:  2009-02-18       Impact factor: 6.868

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