Literature DB >> 15963219

Toxic hepatitis associated with paroxetine.

O Colakoglu1, E Tankurt, B Unsal, F Ugur, A Kupelioglu, Z Buyrac, Z Akpinar.   

Abstract

Hepatotoxicity is a rare complication of paroxetine, a selective serotonin reuptake inhibitor. Regarded as safe in therapeutic use, there have been reports of cases of severe hepatic dysfunction with gross elevations of transaminase levels that may be related to this drug. We report here severe adverse cholestatic and hepatocellular injury in a patient taking paroxetine probably due to an immune-mediated hypersensitivity reaction.

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Year:  2005        PMID： 15963219     DOI： 10.1111/j.1368-5031.2005.00572.x

Source DB:  PubMed          Journal:  Int J Clin Pract        ISSN： 1368-5031            Impact factor:   2.503


  6 in total

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Authors:  Carmen Ferrajolo; Cristina Scavone; Monia Donati; Oscar Bortolami; Giovanna Stoppa; Domenico Motola; Alfredo Vannacci; Alessandro Mugelli; Roberto Leone; Annalisa Capuano
Journal:  Drug Saf       Date:  2018-01       Impact factor: 5.606

2.  Acute hepatitis associated with use of paroxetine.

Authors:  Maurizio Pompili; Paola Tittoto; Roberta Mascianà; Giovanni Gasbarrini; Gian Ludovico Rapaccini
Journal:  Intern Emerg Med       Date:  2008-02-12       Impact factor: 3.397

3.  Clinical associations of hepatic stellate cell (HSC) hyperplasia.

Authors:  Taofic Mounajjed; Rondell P Graham; Schuyler O Sanderson; Thomas C Smyrk
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Review 4.  A consensus statement for safety monitoring guidelines of treatments for major depressive disorder.

Authors:  Seetal Dodd; Gin S Malhi; John Tiller; Isaac Schweitzer; Ian Hickie; Jon Paul Khoo; Darryl L Bassett; Bill Lyndon; Philip B Mitchell; Gordon Parker; Paul B Fitzgerald; Marc Udina; Ajeet Singh; Steven Moylan; Francesco Giorlando; Carolyn Doughty; Christopher G Davey; Michael Theodoros; Michael Berk
Journal:  Aust N Z J Psychiatry       Date:  2011-09       Impact factor: 5.744

Review 5.  Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity.

Authors:  Diogo Telles-Correia; António Barbosa; Helena Cortez-Pinto; Carlos Campos; Nuno B F Rocha; Sérgio Machado
Journal:  World J Gastrointest Pharmacol Ther       Date:  2017-02-06

Review 6.  Antidepressants- and antipsychotics-induced hepatotoxicity.

Authors:  Nevena Todorović Vukotić; Jelena Đorđević; Snežana Pejić; Neda Đorđević; Snežana B Pajović
Journal:  Arch Toxicol       Date:  2021-01-05       Impact factor: 5.153
  6 in total

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