OBJECTIVE: The authors studied the predictive value of six criteria for clinical diagnosis of rabies in living dogs. DESIGN: Identify and test the criteria in a retrospective and prospective study. MATERIAL AND METHOD: Both studies were conducted at the Rabies Diagnostic Unit, Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok. The authors reviewed 1,170 dogs that were kept under observation for 10 days after they exhibited abnormal behavior. To test the predictive value of the six criteria, a prospective study involving 450 rabies suspected dogs was also performed. RESULTS AND CONCLUSION: The six criteria demonstrated 90.2% sensitivity, 96.2% specificity and 94.6% accuracy for the clinical diagnosis of rabies. They can be used for a presumptive diagnosis and may help in prioritizing post-exposure treatments and institute urgent rabies control measures.
OBJECTIVE: The authors studied the predictive value of six criteria for clinical diagnosis of rabies in living dogs. DESIGN: Identify and test the criteria in a retrospective and prospective study. MATERIAL AND METHOD: Both studies were conducted at the Rabies Diagnostic Unit, Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok. The authors reviewed 1,170 dogs that were kept under observation for 10 days after they exhibited abnormal behavior. To test the predictive value of the six criteria, a prospective study involving 450 rabies suspected dogs was also performed. RESULTS AND CONCLUSION: The six criteria demonstrated 90.2% sensitivity, 96.2% specificity and 94.6% accuracy for the clinical diagnosis of rabies. They can be used for a presumptive diagnosis and may help in prioritizing post-exposure treatments and institute urgent rabies control measures.
Authors: Tiziana Lembo; Katie Hampson; Daniel T Haydon; Meggan Craft; Andy Dobson; Jonathan Dushoff; Eblate Ernest; Richard Hoare; Magai Kaare; Titus Mlengeya; Christine Mentzel; Sarah Cleaveland Journal: J Appl Ecol Date: 2008-08 Impact factor: 6.528
Authors: Mark Obonyo; James M Akoko; Austine B Orinde; Eric Osoro; Waqo Gufu Boru; Ian Njeru; Eric M Fèvre Journal: Emerg Infect Dis Date: 2016-03 Impact factor: 6.883
Authors: Katie Hampson; Jonathan Dushoff; Sarah Cleaveland; Daniel T Haydon; Magai Kaare; Craig Packer; Andy Dobson Journal: PLoS Biol Date: 2009-03-10 Impact factor: 8.029