Literature DB >> 15962106

Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin.

Camila Squarzoni Dale1, Rosana de Lima Pagano, Vanessa Rioli.   

Abstract

Hemopressin (PVNFKFLSH), a novel bioactive peptide derived from the alpha1-chain of hemoglobin, was originally isolated from rat brain homogenates. Hemopressin causes hypotension in anesthetized rats and is metabolized in vivo and in vitro by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE). Hemopressin also exerts an antinociceptive action in experimental inflammatory hyperalgesia induced by carrageenin or bradykinin via a mechanism that is independent of opioids. These findings suggest that this peptide may have important regulatory physiological actions in vivo.

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Year:  2005        PMID： 15962106     DOI： 10.1590/s0074-02762005000900017

Source DB:  PubMed          Journal:  Mem Inst Oswaldo Cruz        ISSN： 0074-0276            Impact factor:   2.743


  13 in total

Review 1.  Hemoglobin-derived peptides as novel type of bioactive signaling molecules.

Authors:  Ivone Gomes; Camila S Dale; Kimbie Casten; Miriam A Geigner; Fabio C Gozzo; Emer S Ferro; Andrea S Heimann; Lakshmi A Devi
Journal:  AAPS J       Date:  2010-09-02       Impact factor: 4.009

Review 2.  Hemopressin and other bioactive peptides from cytosolic proteins: are these non-classical neuropeptides?

Authors:  Julia S Gelman; Lloyd D Fricker
Journal:  AAPS J       Date:  2010-04-10       Impact factor: 4.009

3.  Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation in Cpefat/fat mice.

Authors:  Julia S Gelman; Juan Sironi; Leandro M Castro; Emer S Ferro; Lloyd D Fricker
Journal:  J Neurochem       Date:  2010-02-24       Impact factor: 5.372

4.  Interactions between cannabinoid and opioid receptors in a mouse model of diabetic neuropathy.

Authors:  Elaine F Toniolo; Achla Gupta; Adriano C Franciosi; Ivone Gomes; Lakshmi A Devi; Camila S Dale
Journal:  Pain       Date:  2021-10-27       Impact factor: 7.926

5.  Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury.

Authors:  Po-Kuan Chao; Kwok-Tung Lu; Yun-Lin Lee; Jin-Chung Chen; Hung-Li Wang; Yi-Ling Yang; Mei-Yun Cheng; Ming-Feng Liao; Long-Sun Ro
Journal:  PLoS One       Date:  2012-08-24       Impact factor: 3.240

6.  Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors.

Authors:  Kelsey Caetano-Anollés; Justin S Rhodes; Theodore Garland; Sam D Perez; Alvaro G Hernandez; Bruce R Southey; Sandra L Rodriguez-Zas
Journal:  PLoS One       Date:  2016-11-28       Impact factor: 3.240

Review 7.  Intracellular Peptides in Cell Biology and Pharmacology.

Authors:  Christiane B de Araujo; Andrea S Heimann; Ricardo A Remer; Lilian C Russo; Alison Colquhoun; Fábio L Forti; Emer S Ferro
Journal:  Biomolecules       Date:  2019-04-16

8.  Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients.

Authors:  François Dépret; Juliette Amzallag; Adrien Pollina; Laure Fayolle-Pivot; Maxime Coutrot; Maïté Chaussard; Karine Santos; Oliver Hartmann; Marion Jully; Alexandre Fratani; Haikel Oueslati; Alexandru Cupaciu; Mourad Benyamina; Lucie Guillemet; Benjamin Deniau; Alexandre Mebazaa; Etienne Gayat; Boris Farny; Julien Textoris; Matthieu Legrand
Journal:  Crit Care       Date:  2020-04-22       Impact factor: 9.097

9.  Synthesis of hemopressin peptides by classical solution phase fragment condensation.

Authors:  P Anantha Reddy; Sean T Jones; Anita H Lewin; F Ivy Carroll
Journal:  Int J Pept       Date:  2012-11-27

10.  Intragenic antimicrobial peptides (IAPs) from human proteins with potent antimicrobial and anti-inflammatory activity.

Authors:  Guilherme D Brand; Marcelo H S Ramada; Júlia R Manickchand; Rafael Correa; Dalila J S Ribeiro; Michele A Santos; Andreanne G Vasconcelos; Fernando Y Abrão; Maura V Prates; André M Murad; José L Cardozo Fh; José Roberto S A Leite; Kelly G Magalhães; Aline L Oliveira; Carlos Bloch
Journal:  PLoS One       Date:  2019-08-06       Impact factor: 3.240
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