| Literature DB >> 15961439 |
B DasGupta1, K M Konwar, I I Mandoiu, A A Shvartsman.
Abstract
DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.Mesh：
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Year: 2005 PMID： 15961439 DOI： 10.1093/bioinformatics/bti547
Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937