Literature DB >> 15959592

Dynamic kinetic resolution of N-Boc-2-lithiopyrrolidine.

Iain Coldham1, Jignesh J Patel, Graciela Sanchez-Jimenez.   

Abstract

Asymmetric substitution of the organolithium derived either from N-Boc-2-tributylstannylpyrrolidine by tin-lithium exchange or from N-Boc-pyrrolidine by deprotonation occurs in the presence of a commercially available chiral diamine ligand with high levels of enantioselectivity by a dynamic kinetic resolution pathway.

Entities:  

Year:  2005        PMID： 15959592     DOI： 10.1039/b504015a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Enantiomerization dynamics and a catalytic dynamic resolution of N-trimethylallyl-2-lithiopyrrolidine.

Authors:  Timothy K Beng; Taher I Yousaf; Iain Coldham; Robert E Gawley
Journal:  J Am Chem Soc       Date:  2009-05-27       Impact factor: 15.419

2.  The barrier to enantiomerization of N-Boc-2-lithiopyrrolidine: the effect of chiral and achiral diamines.

Authors:  Taher I Yousaf; Roger L Williams; Iain Coldham; Robert E Gawley
Journal:  Chem Commun (Camb)       Date:  2008-01-07       Impact factor: 6.222
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.