Literature DB >> 15957888

Model systems for flavoenzyme activity: site-isolated redox behavior in flavin-functionalized random polystyrene copolymers.

Joseph B Carroll1, Brian J Jordan, Hao Xu, Belma Erdogan, Lisa Lee, Lily Cheng, Christopher Tiernan, Graeme Cooke, Vincent M Rotello.   

Abstract

[reaction: see text] A model system has been developed to study the redox behaviors of flavin derivatives appended onto random polystyrene copolymers through "click" chemistry strategies. The results demonstrate that flavin units attached onto polymers exhibit site-isolated redox behaviors, yielding new materials with electrochemically tunable associations (K(a)(ox) = 450 M(-)(1), K(a)(red) = 18,200 M(-)(1)) to complementary diamidopyridine (DAP) functionality.

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Year:  2005        PMID： 15957888     DOI： 10.1021/ol0505407

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Oxidation of alkyl benzenes by a flavin photooxidation catalyst on nanostructured metal-oxide films.

Authors:  Prateek Dongare; Ian MacKenzie; Degao Wang; David A Nicewicz; Thomas J Meyer
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-11       Impact factor: 11.205

2.  A two stage click-based library of protein tyrosine phosphatase inhibitors.

Authors:  Jian Xie; Christopher T Seto
Journal:  Bioorg Med Chem       Date:  2006-10-12       Impact factor: 3.641

3.  Catalytic Amine Oxidation under Ambient Aerobic Conditions: Mimicry of Monoamine Oxidase B.

Authors:  Alexander T Murray; Myles J H Dowley; Fabienne Pradaux-Caggiano; Amgalanbaatar Baldansuren; Alistair J Fielding; Floriana Tuna; Christopher H Hendon; Aron Walsh; Guy C Lloyd-Jones; Matthew P John; David R Carbery
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-18       Impact factor: 15.336

4.  Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells.

Authors:  Graziele D da Silva; Marina G da Silva; Estrela M P V E Souza; Andersson Barison; Sarah C Simões; Fernando P Varotti; Leandro A Barbosa; Gustavo H R Viana; José A F P Villar
Journal:  Molecules       Date:  2012-08-29       Impact factor: 4.411

5.  Directed Electron Transfer in Flavin Peptides with Oligoproline-Type Helical Conformation as Models for Flavin-Functional Proteins.

Authors:  Samantha Wörner; Julia Leier; Nadine C Michenfelder; Andreas-Neil Unterreiner; Hans-Achim Wagenknecht
Journal:  ChemistryOpen       Date:  2020-12-11       Impact factor: 2.911
  5 in total

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