Literature DB >> 15955958

Reversible impaired memory induced by pulsed methylprednisolone in patients with MS.

I Uttner1, S Müller, C Zinser, M Maier, S Süssmuth, A Claus, B Ostermann, E Elitok, D Ecker, J Brettschneider, R Gold, H Tumani.   

Abstract

Thirty patients with multiple sclerosis were randomized to 500 or 2,000 mg of methylprednisolone (MP) over 5 days. They were prospectively studied neuropsychologically before and at days 6 and 60 after onset of the therapy, using a double-blind study design. Patients showed selective deterioration of declarative memory retrieval at day 6, which was fully reversible at day 60. Although the sample size was small, these effects were independent of the administered MP dose.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15955958     DOI: 10.1212/01.WNL.0000163804.94163.91

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  9 in total

Review 1.  [Effects of high-dose cortisone therapy on cognition].

Authors:  I Uttner; H Tumani
Journal:  Nervenarzt       Date:  2006-06       Impact factor: 1.214

2.  Acute cognitive and behavioral effects of systemic corticosteroids in children treated for inflammatory bowel disease.

Authors:  Christine Mrakotsky; Peter W Forbes; Jane Holmes Bernstein; Richard J Grand; Athos Bousvaros; Eva Szigethy; Deborah P Waber
Journal:  J Int Neuropsychol Soc       Date:  2012-11-19       Impact factor: 2.892

3.  A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.

Authors:  In Young Choi; Laura Piccio; Patra Childress; Bryan Bollman; Arko Ghosh; Sebastian Brandhorst; Jorge Suarez; Andreas Michalsen; Anne H Cross; Todd E Morgan; Min Wei; Friedemann Paul; Markus Bock; Valter D Longo
Journal:  Cell Rep       Date:  2016-05-26       Impact factor: 9.423

4.  Effects of acute relapses on neuropsychological status in multiple sclerosis patients.

Authors:  S A Morrow; S Jurgensen; F Forrestal; Frederick E Munchauer; R H B Benedict
Journal:  J Neurol       Date:  2011-03-08       Impact factor: 4.849

5.  Management of acute exacerbations in multiple sclerosis.

Authors:  Daniel Ontaneda; Alex D Rae-Grant
Journal:  Ann Indian Acad Neurol       Date:  2009-10       Impact factor: 1.383

Review 6.  Cognitive impairment in multiple sclerosis.

Authors:  Alexander Winkelmann; Claudia Engel; Annett Apel; Uwe K Zettl
Journal:  J Neurol       Date:  2007-05       Impact factor: 4.849

Review 7.  Influences on cognition by immunosuppression and immunomodulation in multiple sclerosis.

Authors:  Hayrettin Tumani; Ingo Uttner
Journal:  J Neurol       Date:  2007-05       Impact factor: 4.849

Review 8.  Structural Plasticity of the Hippocampus in Neurodegenerative Diseases.

Authors:  Poornima D E Weerasinghe-Mudiyanselage; Mary Jasmin Ang; Sohi Kang; Joong-Sun Kim; Changjong Moon
Journal:  Int J Mol Sci       Date:  2022-03-20       Impact factor: 5.923

9.  Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer's disease amyloidosis.

Authors:  Yingjie Qi; Igor Klyubin; Tomas Ondrejcak; Neng-Wei Hu; Michael J Rowan
Journal:  Neuropsychopharmacology       Date:  2021-06-29       Impact factor: 7.853

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.