Literature DB >> 15955783

FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded.

Jaime Prilusky1, Clifford E Felder, Tzviya Zeev-Ben-Mordehai, Edwin H Rydberg, Orna Man, Jacques S Beckmann, Israel Silman, Joel L Sussman.   

Abstract

An easy-to-use, versatile and freely available graphic web server, FoldIndex is described: it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the average residue hydrophobicity and net charge of the sequence. FoldIndex has an error rate comparable to that of more sophisticated fold prediction methods. Sliding windows permit identification of large regions within a protein that possess folding propensities different from those of the whole protein.

Mesh:

Substances:

Year:  2005        PMID: 15955783     DOI: 10.1093/bioinformatics/bti537

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  378 in total

1.  Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism.

Authors:  Thomas Dange; David Smith; Tahel Noy; Philipp C Rommel; Lukas Jurzitza; Radames J B Cordero; Anne Legendre; Daniel Finley; Alfred L Goldberg; Marion Schmidt
Journal:  J Biol Chem       Date:  2011-10-24       Impact factor: 5.157

2.  Perfecting precision of predicting prion propensity.

Authors:  Daniel C Masison
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-12       Impact factor: 11.205

Review 3.  Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.

Authors:  Raj Kumar; Iain J McEwan
Journal:  Endocr Rev       Date:  2012-03-20       Impact factor: 19.871

Review 4.  How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis.

Authors:  Joel C Rosenbaum; Richard G Gardner
Journal:  Nucleus       Date:  2011-07-01       Impact factor: 4.197

5.  A systematic survey of in vivo obligate chaperonin-dependent substrates.

Authors:  Kei Fujiwara; Yasushi Ishihama; Kenji Nakahigashi; Tomoyoshi Soga; Hideki Taguchi
Journal:  EMBO J       Date:  2010-04-01       Impact factor: 11.598

6.  LEAPdb: a database for the late embryogenesis abundant proteins.

Authors:  Gilles Hunault; Emmanuel Jaspard
Journal:  BMC Genomics       Date:  2010-04-01       Impact factor: 3.969

Review 7.  Understanding protein non-folding.

Authors:  Vladimir N Uversky; A Keith Dunker
Journal:  Biochim Biophys Acta       Date:  2010-02-01

8.  Functional dissection of an intrinsically disordered protein: understanding the roles of different domains of Knr4 protein in protein-protein interactions.

Authors:  Adilia Dagkessamanskaia; Fabien Durand; Vladimir N Uversky; Matteo Binda; Frédéric Lopez; Karim El Azzouzi; Jean Marie Francois; Hélène Martin-Yken
Journal:  Protein Sci       Date:  2010-07       Impact factor: 6.725

Review 9.  Recent advances in MeCP2 structure and function.

Authors:  Kristopher C Hite; Valerie H Adams; Jeffrey C Hansen
Journal:  Biochem Cell Biol       Date:  2009-02       Impact factor: 3.626

Review 10.  Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins.

Authors:  Deepa Balasubramaniam; Elizabeth A Komives
Journal:  Biochim Biophys Acta       Date:  2012-10-22
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.