Literature DB >> 15953796

Hypercortisolemia and depression.

Charles F Gillespie1, Charles B Nemeroff.   

Abstract

Hypercortisolemia and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis are often found in severe forms of depression. The authors review the history of techniques used to assess the functions of the HPA axis, evidence for hypercortisolemia as a state rather than trait component of depression, and treatment implications.

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Year:  2005        PMID: 15953796     DOI: 10.1097/01.psy.0000163456.22154.d2

Source DB:  PubMed          Journal:  Psychosom Med        ISSN: 0033-3174            Impact factor:   4.312


  95 in total

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Review 8.  Neurosteroid, GABAergic and hypothalamic pituitary adrenal (HPA) axis regulation: what is the current state of knowledge in humans?

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