Literature DB >> 15952949

Body weight gain induced by a newer antipsychotic agent reversed as negative symptoms improved.

M Koga1, K Nakayama.   

Abstract

OBJECTIVE: We describe a patient in whom improvement in negative symptoms contributed to early weight loss and subsequent long-term improvement in weight management.
METHOD: Case report.
RESULTS: A 26-year-old woman with schizophrenia gained 7 kg over the course of 1 year after starting treatment with olanzapine. However, as negative symptoms gradually improved with treatment, she became motivated to diet and exercise regularly. She quickly lost 9 kg and subsequently maintained optimal weight (55 kg; body mass index, 24.1 kg/m(2) ).
CONCLUSION: Important strategies for minimizing weight gain in patients taking antipsychotic agents include improving negative symptoms of avolition and apathy, regular monitoring of body weight and potential medical consequences of overweight and obesity, and educating the patient about the importance of diet and regular exercise.

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Year:  2005        PMID: 15952949     DOI: 10.1111/j.1600-0447.2005.00556.x

Source DB:  PubMed          Journal:  Acta Psychiatr Scand        ISSN: 0001-690X            Impact factor:   6.392


  4 in total

1.  Weight gain in newly diagnosed first-episode psychosis patients and healthy comparisons: one-year analysis.

Authors:  Martin Strassnig; Jean Miewald; Matcheri Keshavan; Rohan Ganguli
Journal:  Schizophr Res       Date:  2007-05-02       Impact factor: 4.939

2.  Positive Symptoms in Antipsychotic-naïve Schizophrenia are Associated with Increased Body Mass Index after Treatment.

Authors:  Shih-Hsien Lin; Huai-Hsuan Tseng; Hsin Chun Tsai; Mei Hung Chi; I Hui Lee; Po See Chen; Kao Chin Chen; Yen Kuang Yang
Journal:  Clin Psychopharmacol Neurosci       Date:  2021-02-28       Impact factor: 2.582

3.  Behavioral outputs of negative symptom domains of schizophrenia.

Authors:  Octavia Căpățînă; Mihaela Fadgyas Stănculete; Ioana Micluția
Journal:  Exp Ther Med       Date:  2021-05-26       Impact factor: 2.447

4.  Deep venous thrombosis and atypical antipsychotics: three cases report.

Authors:  Fatemeh Sheikhmoonesi; Seyyedeh Fatemeh Bahari Saravi
Journal:  Daru       Date:  2012-10-31       Impact factor: 3.117

  4 in total

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