Literature DB >> 15951302

The relative levels of cyclin D1a and D1b alternative transcripts in mantle cell lymphoma may depend more on sample origin than on CCND1 polymorphism.

Nathalie Carrère, Marc-Antoine Belaud-Rotureau, Pierre Dubus, Marie Parrens, Antoine de Mascarel, Jean-Philippe Merlio.   

Abstract

The relative levels of cyclin D1 (CCND1) (a) and (b) transcripts were determined by real-time reverse transcription polymerase chain reaction (RT-PCR) and found to vary according to the tissue origin in both control and tumor samples. A five-fold overexpression of both isoforms was observed in 28/38 cases of mantle cell lymphoma (MCL) and of only one isoform in 10/38 MCL. No correlation was observed between expression of cyclin D1 isoforms and CCND1 genotype at position 870.

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Year:  2005        PMID： 15951302

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  8 in total

1.  The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: p53 alterations and blastoid morphology are strong predictors of a high proliferation index.

Authors:  Julia Slotta-Huspenina; Ina Koch; Laurence de Leval; Gisela Keller; Margit Klier; Karin Bink; Marcus Kremer; Mark Raffeld; Falko Fend; Leticia Quintanilla-Martinez
Journal:  Haematologica       Date:  2012-02-07       Impact factor: 9.941

2.  Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.

Authors:  Michal Marzec; Monika Kasprzycka; Raymond Lai; Andrew B Gladden; Pawel Wlodarski; Ewa Tomczak; Peter Nowell; Samuel E Deprimo; Seth Sadis; Stephen Eck; Stephen J Schuster; J Alan Diehl; Mariusz A Wasik
Journal:  Blood       Date:  2006-05-11       Impact factor: 22.113

3.  Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome.

Authors:  E K A Millar; J L Dean; C M McNeil; S A O'Toole; S M Henshall; T Tran; J Lin; A Quong; C E S Comstock; A Witkiewicz; E A Musgrove; H Rui; L Lemarchand; V W Setiawan; C A Haiman; K E Knudsen; R L Sutherland; E S Knudsen
Journal:  Oncogene       Date:  2009-03-16       Impact factor: 9.867

4.  Identification of the cyclin D1b mRNA variant in mouse.

Authors:  Jack Wu; Si-hung Wu; Aliccia Bollig; Archana Thakur; D Joshua Liao
Journal:  Mol Biol Rep       Date:  2008-04-30       Impact factor: 2.316

5.  t(11;14)-positive mantle cell lymphomas lacking cyclin D1 (CCND1) immunostaining because of a CCND1 mutation or exclusive expression of the CCND1b isoform.

Authors:  Ingram Iaccarino; Lamis Afify; Sietse M Aukema; Katharina Reddemann; Philipp Schütt; Martin Flür; Wolfram Klapper
Journal:  Haematologica       Date:  2018-05-17       Impact factor: 9.941

6.  Relevance of cyclin D1b expression and CCND1 polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma.

Authors:  Sophie Krieger; Juliette Gauduchon; Mikel Roussel; Xavier Troussard; Brigitte Sola
Journal:  BMC Cancer       Date:  2006-10-06       Impact factor: 4.430

7.  Influence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population.

Authors:  Zhenzhen Zeng; Jing Tu; Jin Cheng; Mingjie Yao; Yali Wu; Xiangbo Huang; Xiaomeng Xie; Xiaolei Zhang; Fengmin Lu; Xiangmei Chen
Journal:  Tumour Biol       Date:  2015-04-08

8.  Consequence of the tumor-associated conversion to cyclin D1b.

Authors:  Michael A Augello; Lisa D Berman-Booty; Richard Carr; Akihiro Yoshida; Jeffry L Dean; Matthew J Schiewer; Felix Y Feng; Scott A Tomlins; Erhe Gao; Walter J Koch; Jeffrey L Benovic; John Alan Diehl; Karen E Knudsen
Journal:  EMBO Mol Med       Date:  2015-05       Impact factor: 12.137
  8 in total

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