| Literature DB >> 15951214 |
Petra Hoffmann1, Tina J Boeld, Biserka Piseshka, Matthias Edinger.
Abstract
Graft-versus-host disease is a major complication after allogeneic bone marrow transplantation (BMT) caused by donor T cells. Immunosuppression mediated by CD4(+)CD25(+) regulatory T cells has been shown to ameliorate such pathogenic immune responses in animal models. Here, we summarize recent findings from experimental and clinical studies and propose a model for peripheral tolerance induction after BMT.Entities:
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Year: 2005 PMID： 15951214 DOI： 10.1016/j.micinf.2005.03.035
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700