Literature DB >> 15951174

Synthesis of cationic beta-vinyl substituted meso-tetraphenylporphyrins and their in vitro activity against herpes simplex virus type 1.

Eduarda M P Silva1, Francesca Giuntini, Maria A F Faustino, João P C Tomé, Maria G P M S Neves, Augusto C Tomé, Artur M S Silva, Maria G Santana-Marques, António J Ferrer-Correia, José A S Cavaleiro, Maria F Caeiro, Ricardo R Duarte, Sabina A P Tavares, Inês N Pegado, Bruno d'Almeida, António P A De Matos, Maria L Valdeira.   

Abstract

An easy route to cationic beta-vinyl substituted meso-tetraphenylporphyrin derivatives is described. Two novel compounds were tested in vitro for their antiviral photoactivity against herpes simplex virus type 1. One of these compounds exhibited a significant activity, reaching 99% of virus inactivation after 15 min of photoactivation.

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Year:  2005        PMID： 15951174     DOI： 10.1016/j.bmcl.2005.05.044

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

Review 1.  Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents.

Authors:  Nela Malatesti; Ivana Munitic; Igor Jurak
Journal:  Biophys Rev       Date:  2017-03-24

2.  Characterization of isomeric cationic porphyrins with beta-pyrrolic substituents by electrospray mass spectrometry: the singular behavior of a potential virus photoinactivator.

Authors:  Raul A Izquierdo; Cristina M Barros; M Graça Santana-Marques; A J Ferrer-Correia; Eduarda M P Silva; Francesca Giuntini; Maria A F Faustino; João P C Tomé; Augusto C Tomé; Artur M S Silva; Graça P M S Neves; J A S Cavaleiro; Andreia F Peixoto; Mariette M Pereira; Alberto A C C Pais
Journal:  J Am Soc Mass Spectrom       Date:  2006-10-27       Impact factor: 3.109

3.  Interaction of cationic meso-porphyrins with liposomes, mitochondria and erythrocytes.

Authors:  Fabio M Engelmann; Ildemar Mayer; Dino S Gabrielli; Henrique E Toma; Alicia J Kowaltowski; Koiti Araki; Mauricio S Baptista
Journal:  J Bioenerg Biomembr       Date:  2007-04-14       Impact factor: 3.853

Review 4.  β-Formyl- and β-Vinylporphyrins: Magic Building Blocks for Novel Porphyrin Derivatives.

Authors:  Ana F R Cerqueira; Nuno M M Moura; Vanda Vaz Serra; M Amparo F Faustino; Augusto C Tomé; José A S Cavaleiro; M Graça P M S Neves
Journal:  Molecules       Date:  2017-07-29       Impact factor: 4.411

Review 5.  Photodynamic inactivation of mammalian viruses and bacteriophages.

Authors:  Liliana Costa; Maria Amparo F Faustino; Maria Graça P M S Neves; Angela Cunha; Adelaide Almeida
Journal:  Viruses       Date:  2012-06-26       Impact factor: 5.048

6.  Antimicrobial Photodynamic Therapy in the Control of COVID-19.

Authors:  Adelaide Almeida; M Amparo F Faustino; Maria G P M S Neves
Journal:  Antibiotics (Basel)       Date:  2020-06-11

7.  Novel Cationic Meso-Arylporphyrins and Their Antiviral Activity against HSV-1.

Authors:  Kseniya A Zhdanova; Inga O Savelyeva; Artem V Ezhov; Andrey P Zhdanov; Konstantin Yu Zhizhin; Andrey F Mironov; Natal'ya A Bragina; Alla A Babayants; Irina S Frolova; Nadezhda I Filippova; Nadezhda N Scliankina; Olga N Scheglovitova
Journal:  Pharmaceuticals (Basel)       Date:  2021-03-08

8.  A Comparison of Porphyrin Photosensitizers in Photodynamic Inactivation of RNA and DNA Bacteriophages.

Authors:  Joe Heffron; Matthew Bork; Brooke K Mayer; Troy Skwor
Journal:  Viruses       Date:  2021-03-23       Impact factor: 5.048

9.  Antimicrobial Photodynamic Approach in the Inactivation of Viruses in Wastewater: Influence of Alternative Adjuvants.

Authors:  Maria Bartolomeu; Cristiana Oliveira; Carla Pereira; M Graça P M S Neves; M Amparo F Faustino; Adelaide Almeida
Journal:  Antibiotics (Basel)       Date:  2021-06-24
  9 in total

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