| Literature DB >> 15951173 |
Trent D Ashton1, Peter J Scammells.
Abstract
Synthesis of 5'-fluoro-5'-deoxyadenosine (5'-FDA) and structurally similar compounds is generally a poor yielding process. This is attributed to the instability of the selected synthetic intermediates. Herein, we report a general synthesis of 5'-fluoro-5'-deoxy-N6-substituted adenosines including a high yielding access to 5'-FDA.Entities:
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Year: 2005 PMID： 15951173 DOI： 10.1016/j.bmcl.2005.05.029
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823