| Literature DB >> 15950784 |
Alexis Bailey1, Vadim Yuferov, Jacob Bendor, Stefan D Schlussman, Yan Zhou, Ann Ho, Mary Jeanne Kreek.
Abstract
An increase in preprodynorphin (ppdyn) mRNA was detected in the caudate putamen of chronically cocaine-treated and 3-h withdrawn rats. An increase in mu-opioid receptor (MOP) mRNA levels was observed in the frontal cortex of 3-h withdrawn rats. Naloxone had no effect on the increase of MOP or ppdyn mRNA levels. The results indicate that the opioid system is altered during early withdrawal from chronic cocaine administration.Entities:
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Year: 2005 PMID: 15950784 DOI: 10.1016/j.molbrainres.2005.02.017
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN: 0169-328X