Literature DB >> 15950665

Growth hormone secretion and insulin-like growth factor-1 are related to hyperandrogenism in nonobese patients with polycystic ovary syndrome.

Ana Cristina Premoli1, Laura Ferreira Santana, Rui Alberto Ferriani, Marcos Dias de Moura, Marcos Felipe Silva De Sá, Rosana Maria dos Reis.   

Abstract

Women of normal weight with polycystic ovary syndrome (PCOS) and hyperinsulinemia presented high growth hormone (GH) levels in response to the l-dopa test, suggesting that the action of GH and insulin-like growth factor-1 (IGF-1) might be responsible for the elevation in LH and the consequent hyperandrogenic anovulation observed in normal weight women with PCOS. Insulin resistance and obesity are related to a reduction in GH secretion in obese women with PCOS.

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Year:  2005        PMID： 15950665     DOI： 10.1016/j.fertnstert.2004.10.057

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  7 in total

1.  MiRNA-99a can regulate proliferation and apoptosis of human granulosa cells via targeting IGF-1R in polycystic ovary syndrome.

Authors:  Yudi Geng; Cong Sui; Yang Xun; Qiaohong Lai; Lei Jin
Journal:  J Assist Reprod Genet       Date:  2018-10-29       Impact factor: 3.412

2.  Trans-omics analyses revealed differences in hormonal and nutritional status between wild and cultured female Japanese eel (Anguilla japonica).

Authors:  Masato Higuchi; Miyuki Mekuchi; Takeshi Hano; Hitoshi Imaizumi
Journal:  PLoS One       Date:  2019-05-09       Impact factor: 3.240

3.  LKB1 suppresses androgen synthesis in a mouse model of hyperandrogenism via IGF-1 signaling.

Authors:  Ying Xu; Yongxing Gao; Zufang Huang; Yan Zheng; Wenjuan Teng; Deyan Zheng; Xiaohua Zheng
Journal:  FEBS Open Bio       Date:  2019-09-12       Impact factor: 2.693

4.  Down-regulated lncRNA HOTAIR alleviates polycystic ovaries syndrome in rats by reducing expression of insulin-like growth factor 1 via microRNA-130a.

Authors:  Bin Jiang; Min Xue; Dabao Xu; Jiayu Song; Shujuan Zhu
Journal:  J Cell Mol Med       Date:  2019-11-16       Impact factor: 5.310

5.  miR-483 is Down-Regulated in Polycystic Ovarian Syndrome and Inhibits KGN Cell Proliferation via Targeting Insulin-Like Growth Factor 1 (IGF1).

Authors:  Yungai Xiang; Yuxia Song; Yan Li; Dongmei Zhao; Liying Ma; Li Tan
Journal:  Med Sci Monit       Date:  2016-09-23

6.  Effects of vitamin D supplementation on follicular development, gonadotropins and sex hormone concentrations, and insulin resistance in induced polycystic ovary syndrome.

Authors:  Nasim Behmanesh; Ali Abedelahi; Hojjatollah Nozad Charoudeh; Alireza Alihemmati
Journal:  Turk J Obstet Gynecol       Date:  2019-10-10

7.  The extract of concentrated growth factor enhances osteogenic activity of osteoblast through PI3K/AKT pathway and promotes bone regeneration in vivo.

Authors:  Kai Dong; Wen-Juan Zhou; Zhong-Hao Liu; Peng-Jie Hao
Journal:  Int J Implant Dent       Date:  2021-08-04
  7 in total

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