Literature DB >> 15950381

Light response differences in the superior colliculus of albino and pigmented rats.

Biju B Thomas1, Robert B Aramant, Srinivas R Sadda, Magdalene J Seiler.   

Abstract

Multi-unit visual responses to light intensities ranging from -6.46 to 0.81 logcd/m2 were recorded from the surface of the superior colliculus of dark-adapted normal pigmented and normal albino rats. Light sensitivity was significantly higher in albinos. The response onset latency was inversely proportional to the stimulus intensity. The progression of the stimulus intensity versus response onset latency curve showed a considerable difference between pigmented and albino rats. At low light levels, longer response onset latencies were recorded in pigmented rats than in albinos. This can be attributed to the transmission of rod-driven responses. The differences observed in the light response characteristics of albino rats may be indicative of their visual abnormalities.

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Year:  2005        PMID: 15950381     DOI: 10.1016/j.neulet.2005.05.034

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  17 in total

Review 1.  Cell replacement and visual restoration by retinal sheet transplants.

Authors:  Magdalene J Seiler; Robert B Aramant
Journal:  Prog Retin Eye Res       Date:  2012-07-05       Impact factor: 21.198

2.  Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats with Severe Retinal Degeneration.

Authors:  Andrzej T Foik; Georgina A Lean; Leo R Scholl; Bryce T McLelland; Anuradha Mathur; Robert B Aramant; Magdalene J Seiler; David C Lyon
Journal:  J Neurosci       Date:  2018-11-05       Impact factor: 6.167

3.  Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration.

Authors:  M J Seiler; B W Jones; R B Aramant; P B Yang; H S Keirstead; R E Marc
Journal:  Eur J Neurosci       Date:  2012-05-17       Impact factor: 3.386

4.  A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.

Authors:  Biju B Thomas; Danhong Zhu; Tai-Chi Lin; Young Chang Kim; Magdalene J Seiler; Juan Carlos Martinez-Camarillo; Bin Lin; Yousuf Shad; David R Hinton; Mark S Humayun
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-09-13       Impact factor: 3.117

5.  Visual restoration and transplant connectivity in degenerate rats implanted with retinal progenitor sheets.

Authors:  M J Seiler; R B Aramant; B B Thomas; Q Peng; S R Sadda; H S Keirstead
Journal:  Eur J Neurosci       Date:  2010-01-25       Impact factor: 3.386

6.  Behavioral evaluation of visual function of rats using a visual discrimination apparatus.

Authors:  Biju B Thomas; Deedar M Samant; Magdalene J Seiler; Robert B Aramant; Sharzad Sheikholeslami; Kevin Zhang; Zhenhai Chen; SriniVas R Sadda
Journal:  J Neurosci Methods       Date:  2006-12-28       Impact factor: 2.390

7.  Rat strain differences in startle gating-disruptive effects of apomorphine occur with both acoustic and visual prepulses.

Authors:  M Weber; N R Swerdlow
Journal:  Pharmacol Biochem Behav       Date:  2007-09-07       Impact factor: 3.533

8.  Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials.

Authors:  Peter Heiduschka; Ulrich Schraermeyer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-07-25       Impact factor: 3.117

9.  Absorption-mode Fourier transform mass spectrometry: the effects of apodization and phasing on modified protein spectra.

Authors:  Yulin Qi; Huilin Li; Rebecca H Wills; Pilar Perez-Hurtado; Xiang Yu; David P A Kilgour; Mark P Barrow; Cheng Lin; Peter B O'Connor
Journal:  J Am Soc Mass Spectrom       Date:  2013-04-09       Impact factor: 3.109

10.  Short and long term axotomy-induced ERG changes in albino and pigmented rats.

Authors:  Luis Alarcón-Martínez; Pedro de la Villa; Marcelino Avilés-Trigueros; Román Blanco; Maria P Villegas-Pérez; Manuel Vidal-Sanz
Journal:  Mol Vis       Date:  2009-11-17       Impact factor: 2.367

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