Literature DB >> 15950326

Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid.

Alessandra Ammazzalorso1, Rosa Amoroso, Mario Baraldi, Giancarlo Bettoni, Daniela Braghiroli, Barbara De Filippis, Letizia Giampietro, Maria L Tricca, Francesca Vezzalini.   

Abstract

The thiophene-, benzothiazole- and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100 analyzer using bull blood.

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Year:  2005        PMID: 15950326     DOI: 10.1016/j.ejmech.2005.03.022

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  2 in total

1.  The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami.

Authors:  Annalisa Chiavaroli; Viviana di Giacomo; Barbara De Filippis; Amelia Cataldi; Claudio Ferrante; Letizia Giampietro
Journal:  Molecules       Date:  2022-07-30       Impact factor: 4.927

2.  Biological activities of 2-mercaptobenzothiazole derivatives: a review.

Authors:  Mohammed Afzal Azam; Bhojraj Suresh
Journal:  Sci Pharm       Date:  2012-06-18
  2 in total

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