| Literature DB >> 15949865 |
Abstract
Vertebrates use many different strategies to determine sex, but the Sox9 gene is a common thread, probably acting as the pivotal gene that controls the male-determining pathway. It now appears that Sox9 is not alone in this role, and that a closely related gene, Sox8, can partly substitute for Sox9. But is this a clever backup strategy to safeguard male development, or a relic of the past?Entities:
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Year: 2005 PMID： 15949865 DOI： 10.1016/j.tig.2005.05.006
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639