Literature DB >> 15945435

Chondroblastoma of the lumbar spine. Report of two cases and review of the literature.

Raphaël Vialle1, Antoine Feydy, Ludovic Rillardon, Carla Tohme-Noun, Philippe Anract, Magali Colombat, Gonzague De Pinieux, Jean-Luc Drapé, Pierre Guigui.   

Abstract

Chondroblastoma is a benign cartilaginous neoplasm that generally affects the appendicular skeleton. Twenty-six cases of spinal chondroblastoma have been reported in the past 50 years, only six of which were located in the lumbar region. The authors report two cases involving this exceptional location. In both patients, low-back pain, in the absence of radicular pain, was the presenting symptom. In both cases, plain radiography and computerized tomography scanning revealed an osteolytic lesion surrounded by marginal sclerosis. Magnetic resonance imaging allowed the authors to study the tumor's local extension. Examination of a percutaneous fluoroscopy-guided biopsy sample revealed the following typical histological features of chondroblastoma: chondroid tissue, focally alternating with cellular areas, and no nuclear atypia or pleomorphism. To reduce the risk of local recurrence, vertebrectomy and anterior-posterior fusion were performed in both cases. In one case, a structural lumbar scoliosis was corrected during the posterior procedure. There was no postoperative complication. No recurrence was observed during the 3- to 6-year follow-up period. The surgery-related results were deemed successful. Although exceptional, the diagnosis of chondroblastoma is possible in lesions involving the lumbar spine. Other spinal locations are described in the literature, and frequency of recurrence is stressed. A vertebrectomy is advised to reduce the risk of local recurrence.

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Year:  2005        PMID: 15945435     DOI: 10.3171/spi.2005.2.5.0596

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  3 in total

1.  Missed radiographic and clinical findings in a case of non-idiopathic scoliosis resulting from chondroblastoma.

Authors:  Navraj S Sagoo; Edward P Southern; Andrew G King; Matthew W Stark; Lori A McBride
Journal:  Spine Deform       Date:  2020-08-21

2.  Clinical features, treatments and long-term follow-up outcomes of spinal chondroblastoma: report of 13 clinical cases in a single center.

Authors:  Qi Jia; Chao Liu; Jian Yang; Yong Ji; Haifeng Wei; Tielong Liu; Xinghai Yang; Cheng Yang; Jianru Xiao
Journal:  J Neurooncol       Date:  2018-07-02       Impact factor: 4.130

3.  Sacral chondroblastoma - a rare location, a rare pathology: A case report and review of literature.

Authors:  Bo-Wen Zheng; Hua-Qing Niu; Xiao-Bin Wang; Jing Li
Journal:  World J Clin Cases       Date:  2021-07-16       Impact factor: 1.337

  3 in total

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