Literature DB >> 15945140

Ball lens coupled fiber-optic probe for depth-resolved spectroscopy of epithelial tissue.

Richard A Schwarz1, Dizem Arifler, Sung K Chang, Ina Pavlova, Insiya A Hussain, Vivian Mack, Bob Knight, Rebecca Richards-Kortum, Ann M Gillenwater.   

Abstract

A ball lens coupled fiber-optic probe design is described for depth-resolved measurements of the fluorescence and reflectance properties of epithelial tissue. A reflectance target, fluorescence targets, and a two-layer tissue phantom consisting of fluorescent microspheres suspended in collagen are used to characterize the performance of the probe. Localization of the signal to within 300 microm of the probe tip is observed by use of reflectance and fluorescence targets in air. Differential enhancement of the fluorescence signal from the top layer of the two-layer tissue phantom is observed.

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Year:  2005        PMID： 15945140      PMCID： PMC2773162          DOI： 10.1364/ol.30.001159

Source DB:  PubMed          Journal:  Opt Lett        ISSN： 0146-9592            Impact factor:   3.776


  12 in total

1.  Realistic three-dimensional epithelial tissue phantoms for biomedical optics.

Authors:  Konstantin Sokolov; Javier Galvan; Alexey Myakov; Alicia Lacy; Rueben Lotan; Rebecca Richards-Kortum
Journal:  J Biomed Opt       Date:  2002-01       Impact factor: 3.170

2.  Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation.

Authors:  Changfang Zhu; Quan Liu; Nirmala Ramanujam
Journal:  J Biomed Opt       Date:  2003-04       Impact factor: 3.170

3.  Selective detection of fluorophore layers in turbid media: the role of fiber-optic probe design.

Authors:  T Joshua Pfefer; L Stephanie Matchette; Amanda M Ross; Marwood N Ediger
Journal:  Opt Lett       Date:  2003-01-15       Impact factor: 3.776

4.  Optical fiber probe for biomedical Raman spectroscopy.

Authors:  Jason T Motz; Martin Hunter; Luis H Galindo; Joseph A Gardecki; John R Kramer; Ramachandra R Dasari; Michael S Feld
Journal:  Appl Opt       Date:  2004-01-20       Impact factor: 1.980

Review 5.  Fiber optic probes for biomedical optical spectroscopy.

Authors:  Urs Utzinger; Rebecca R Richards-Kortum
Journal:  J Biomed Opt       Date:  2003-01       Impact factor: 3.170

6.  Single-scattering spectroscopy for the endoscopic analysis of particle size in superficial layers of turbid media.

Authors:  Arjen Amelink; Martin P L Bard; Sjaak A Burgers; Henricus J C M Sterenborg
Journal:  Appl Opt       Date:  2003-07-01       Impact factor: 1.980

7.  Multiple-fiber probe design for fluorescence spectroscopy in tissue.

Authors:  T Joshua Pfefer; Kevin T Schomacker; Marwood N Ediger; Norman S Nishioka
Journal:  Appl Opt       Date:  2002-08-01       Impact factor: 1.980

8.  Optical sectioning using a fiber probe with an angled illumination-collection geometry: evaluation in engineered tissue phantoms.

Authors:  Linda Nieman; Alexey Myakov; Jesse Aaron; Konstantin Sokolov
Journal:  Appl Opt       Date:  2004-02-20       Impact factor: 1.980

9.  Fiber-optic bundle design for quantitative fluorescence measurement from tissue.

Authors:  B W Pogue; G Burke
Journal:  Appl Opt       Date:  1998-11-01       Impact factor: 1.980

10.  Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers.

Authors:  Melissa C Skala; Gregory M Palmer; Changfang Zhu; Quan Liu; Kristin M Vrotsos; Crystal L Marshek-Stone; Annette Gendron-Fitzpatrick; Nirmala Ramanujam
Journal:  Lasers Surg Med       Date:  2004       Impact factor: 4.025
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  18 in total

1.  Reflectance spectroscopy for diagnosis of epithelial precancer: model-based analysis of fiber-optic probe designs to resolve spectral information from epithelium and stroma.

Authors:  Dizem Arifler; Richard A Schwarz; Sung K Chang; Rebecca Richards-Kortum
Journal:  Appl Opt       Date:  2005-07-10       Impact factor: 1.980

2.  Autofluorescence and diffuse reflectance spectroscopy of oral epithelial tissue using a depth-sensitive fiber-optic probe.

Authors:  Richard A Schwarz; Wen Gao; Dania Daye; Michelle D Williams; Rebecca Richards-Kortum; Ann M Gillenwater
Journal:  Appl Opt       Date:  2008-02-20       Impact factor: 1.980

3.  Performance of a lookup table-based approach for measuring tissue optical properties with diffuse optical spectroscopy.

Authors:  Brandon S Nichols; Narasimhan Rajaram; James W Tunnell
Journal:  J Biomed Opt       Date:  2012-05       Impact factor: 3.170

4.  Lensed fiber-optic probe design for efficient photon collection in scattering media.

Authors:  Youngjae Ryu; Younghoon Shin; Dasol Lee; Judith Y Altarejos; Euiheon Chung; Hyuk-Sang Kwon
Journal:  Biomed Opt Express       Date:  2014-12-17       Impact factor: 3.732

5.  A fiber optic probe design to measure depth-limited optical properties in-vivo with low-coherence enhanced backscattering (LEBS) spectroscopy.

Authors:  Nikhil N Mutyal; Andrew Radosevich; Bradley Gould; Jeremy D Rogers; Andrew Gomes; Vladimir Turzhitsky; Vadim Backman
Journal:  Opt Express       Date:  2012-08-27       Impact factor: 3.894

6.  Optical technologies and molecular imaging for cervical neoplasia: a program project update.

Authors:  Timon P H Buys; Scott B Cantor; Martial Guillaud; Karen Adler-Storthz; Dennis D Cox; Clement Okolo; Oyedunni Arulogon; Oladimeji Oladepo; Karen Basen-Engquist; Eileen Shinn; José-Miguel Yamal; J Robert Beck; Michael E Scheurer; Dirk van Niekerk; Anais Malpica; Jasenka Matisic; Gregg Staerkel; Edward Neely Atkinson; Luc Bidaut; Pierre Lane; J Lou Benedet; Dianne Miller; Tom Ehlen; Roderick Price; Isaac F Adewole; Calum MacAulay; Michele Follen
Journal:  Gend Med       Date:  2011-09-22

7.  Depth-resolved measurements with elliptically polarized reflectance spectroscopy.

Authors:  Maria J Bailey; Konstantin Sokolov
Journal:  Biomed Opt Express       Date:  2016-06-28       Impact factor: 3.732

8.  Comparison of multispectral wide-field optical imaging modalities to maximize image contrast for objective discrimination of oral neoplasia.

Authors:  Darren Roblyer; Cristina Kurachi; Vanda Stepanek; Richard A Schwarz; Michelle D Williams; Adel K El-Naggar; J Jack Lee; Ann M Gillenwater; Rebecca Richards-Kortum
Journal:  J Biomed Opt       Date:  2010 Nov-Dec       Impact factor: 3.170

9.  Design and microfabrication of a miniature fiber optic probe with integrated lenses and mirrors for Raman and fluorescence measurements.

Authors:  Thitaphat Ngernsutivorakul; Cynthia M Cipolla; Colleen E Dugan; Shi Jin; Michael D Morris; Robert T Kennedy; Francis W L Esmonde-White
Journal:  Anal Bioanal Chem       Date:  2016-10-20       Impact factor: 4.142

10.  Analytical light reflectance models for overlapping illumination and collection area geometries.

Authors:  Andrew J Gomes; Vadim Backman
Journal:  Appl Opt       Date:  2012-11-20       Impact factor: 1.980
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