Literature DB >> 15944999

Central corneal thickness in primary open angle glaucoma, pseudoexfoliative glaucoma, ocular hypertension, and normal population.

R Yagci1, U Eksioglu, I Midillioglu, I Yalvac, E Altiparmak, S Duman.   

Abstract

PURPOSE: This study was designed to determine the relationship between central corneal thickness (CCT) and intraocular pressure (IOP) measured by applanation tonometer in glaucomatous, ocular hypertensive, and normal eyes.
METHODS: A total of 125 subjects were included in the study. Twenty-six had primary open angle glaucoma (POAG), 25 had pseudoexfoliative glaucoma (PXG), 24 had ocular hypertension (OHT), and 50 of them were normal. IOP values were measured by Goldmann applanation tonometer whereas CCT values were measured by ultrasonic pachymeter.
RESULTS: CCT values in the OHT group (595.75+/-22.52 microm) were greater than the CCT values of the POAG group (539.92+/-21.50 microm), the PXG group (526.28+/-31.73 microm), and the normal group (533.96+/-29.25 microm) (p<0.05). Eight patients who were diagnosed with OHT showed IOP values of 21 mm Hg or lower with corrected IOP values according to CCT.
CONCLUSIONS: Increased CCT may lead to falsely high values of IOP measured with Goldmann applanation tonometer. In this study, when IOP values of the OHT group were redefined according to the formulae regarding the CCT, the authors noted that one third of them were normal. Determination of the CCT in OHT cases is crucial since it has great impact on IOP values, measured with applanation tonometer, which is the main parameter in the diagnosis and follow-up of glaucoma.

Entities:  

Mesh:

Year:  2005        PMID: 15944999     DOI: 10.1177/112067210501500302

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  7 in total

1.  Corneal biomechanical properties in exfoliation syndrome and exfoliation glaucoma.

Authors:  Zisis Gatzioufas; Berthold Seitz
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-04-21       Impact factor: 3.117

2.  Central corneal thickness in newly diagnosed glaucoma patients in South West Ethiopia: a cross-sectional study.

Authors:  Kumale Tolesa; Girum W Gessesse
Journal:  BMC Ophthalmol       Date:  2016-08-31       Impact factor: 2.209

3.  No differences in central corneal thickness between open-angle and pseudoexfoliation glaucoma patients.

Authors:  Marcelo Ayala; Johanna Karlsson
Journal:  Clin Ophthalmol       Date:  2017-04-19

4.  The impact of central corneal thickness on intraocular pressure among Ethiopian glaucoma patients: a cross-sectional study.

Authors:  Yeshigeta Gelaw
Journal:  BMC Ophthalmol       Date:  2012-11-27       Impact factor: 2.209

5.  Central corneal thickness in subjects with glaucoma and in normal individuals (with or without pseudoexfoliation syndrome).

Authors:  Georgios Kitsos; Christos Gartzios; Ioannis Asproudis; Eleni Bagli
Journal:  Clin Ophthalmol       Date:  2009-10-19

6.  Evaluation of the endothelial cell density and the central corneal thickness in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

Authors:  Bożydar T Tomaszewski; Renata Zalewska; Zofia Mariak
Journal:  J Ophthalmol       Date:  2014-07-01       Impact factor: 1.909

7.  Diurnal variation in central corneal thickness and intraocular pressure in eyes with pseudoexfoliation syndrome without glaucoma.

Authors:  Stuart Keel; Linda Malesic; Siew-Pang Chan
Journal:  Indian J Ophthalmol       Date:  2014-11       Impact factor: 1.848

  7 in total

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