Modest increase in seasonal allergic rhinitis and eczema over 8 years among Estonian schoolchildren.

We studied time trends in the prevalence of asthma and allergic diseases in Estonian children born before and after the collapse of the Soviet Union, as this event markedly altered the lifestyle in Estonia. Two identical cross-sectional studies were performed as part of phase I and phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Children, aged 6-7 yr (n = 3070 in 1993-94 and 2383 in 2001-02) and 13-14 yr (n = 3476 and 3576, respectively), completed ISAAC core-written questionnaires, and 13-14-yr olds (n = 3427 and 3259, respectively) also video questionnaires. The prevalence of respiratory symptoms was mostly similar in the two studies. Despite this, the prevalence of diagnosed asthma increased. This was probably due to modified diagnostic criteria and increased awareness. Furthermore, the prevalence of rhinitis during the pollen season increased, e.g., rhinitis in May from 1.7% to 3.5%; sex-adjusted prevalence odds ratio (POR) 2.09 (95% confidence interval 1.47-2.96) in 6-7-yr olds, and from 2.6% to 5.5%; POR 2.22 (1.72-2.87) in 13-14-yr olds. The prevalence of flexural dermatitis also increased from 12.0% to 13.5%; POR 1.20 (1.02-1.41) in 6-7-yr olds, and from 7.7% to 9.4%; POR 1.26 (1.07-1.50) in 13-14-yr olds. The increase was similar in children born before and after the regaining of Estonian independence, indicating that the influence of factors related to a Western lifestyle and affecting the prevalence of allergic symptoms is not restricted to infancy, but may be operative throughout childhood.