| Literature DB >> 15943544 |
William E Pelham1, Lisa Burrows-Maclean, Elizabeth M Gnagy, Gregory A Fabiano, Erika K Coles, Katy E Tresco, Anil Chacko, Brian T Wymbs, Amber L Wienke, Kathryn S Walker, Martin T Hoffman.
Abstract
Stimulant medication and behavioral treatments are evidence-based for children with attention-deficit/hyperactivity disorder, but the combination of the 2 treatments has been understudied. In this investigation, methylphenidate (MPH) was crossed with 2 levels of behavior modification (BMOD) in a summer treatment program. Twenty-seven children with attention-deficit/hyperactivity disorder, aged 6-12, participated. Children received placebo and 3 doses of transdermal MPH (12.5 cm(2), 25.0 cm(2), and 37.5 cm(2)). BMOD was implemented on alternating weeks. Both treatments produced large and significant effects. Combined treatment was superior to either treatment alone. The effects of transdermal MPH were comparable to those found in this setting in previous studies with multiple stimulant medications and formulations. Consistent with other research, low doses of MPH--even lower than in previous studies--yielded enhanced effects in combination with behavior modification. Copyright 2005 APA, all rights reserved.Entities:
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Year: 2005 PMID： 15943544 DOI： 10.1037/1064-1297.13.2.111
Source DB: PubMed Journal: Exp Clin Psychopharmacol ISSN： 1064-1297 Impact factor: 3.157