Literature DB >> 15943122

A clinical trial to assess the use of sodium hypochlorite and oxytetracycline on the healing of digital dermatitis lesions in cattle.

Luiz A F Silva1, Carla A Silva, José R J Borges, Maria C S Fioravanti, Gabriela T Borges, Ingrid B Atayde.   

Abstract

The increased frequency of diseases, especially those of the hoof, cause economic losses, such as premature culling of affected animals, decreased milk production, weight loss, reduced fertility, and the high costs of treatment. A great variety of hoof conditions may affect cattle, one of them is digital dermatitis. These conditions are probably due to multiple factorial diseases and present with similar clinical signs. Bovine lameness is typically treated by foot trimming and debridment of the lesions, coupled when necessary with systemic antibiotics and therapeutic footbaths, which results in a clinical cure in the majority of the cases. The objective of this study was to evaluate the topical action of sodium hypochlorite associated with the systemic use of oxytetracycline for the treatment of wounds clinically diagnosed as bovine digital dermatitis. One hundred and twenty Holstein cattle varying ages from 1 to 9 y and presenting the clinical signs of digital dermatitis, were used in this study. Group 1 (G1) received topical treatment with a 1% sodium hypochlorite footbath twice a day for 30 d and 4 treatments of parenteral oxytetracycline (10 mg/kg bodyweight, IM, q48h). Group 2 (G2) received only the topical treatment with 1% sodium hypochlorite, as described for G1. Group 3 (G3) received only with parenteral oxytetracycline, as described for G1. Group 4 (G4) was treated exclusively with a dicloro divynil pirrolidona, ortoiododimetil, para-nitofenil-fosforotioato in a vegetal tar-based ointment, immediately after the surgery. After 45 d, the recovery rates were as follows: G1, 86.67%; G2, 73.33%; G3, 56.67%; and G4, 50%. The surgical treatment of digital dermatitis with subsequent treatment with oxytetracycline systemically and 1% sodium hypochlorite topically was the most effective for the convalescence of cattle bearing wounds similar to digital dermatitis.

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Year:  2005        PMID: 15943122      PMCID: PMC1082879     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  3 in total

1.  Observations on the pathogenesis of digital dermatitis in cattle.

Authors:  R W Blowey; S H Done; W Cooley
Journal:  Vet Rec       Date:  1994-07-30       Impact factor: 2.695

2.  Spirochete-associated bovine digital dermatitis.

Authors:  I E Borgmann; J Bailey; E G Clark
Journal:  Can Vet J       Date:  1996-01       Impact factor: 1.008

3.  Digital dermatitis: report of an outbreak.

Authors:  S R van Amstel; S van Vuuren; C L Tutt
Journal:  J S Afr Vet Assoc       Date:  1995-09       Impact factor: 1.474

  3 in total
  3 in total

1.  Deep sequencing analysis reveals temporal microbiota changes associated with development of bovine digital dermatitis.

Authors:  Adam C Krull; Jan K Shearer; Patrick J Gorden; Vickie L Cooper; Gregory J Phillips; Paul J Plummer
Journal:  Infect Immun       Date:  2014-05-27       Impact factor: 3.441

Review 2.  Digital Dermatitis in Cattle: Current Bacterial and Immunological Findings.

Authors:  Jennifer H Wilson-Welder; David P Alt; Jarlath E Nally
Journal:  Animals (Basel)       Date:  2015-11-11       Impact factor: 2.752

3.  A Highly Effective Protocol for the Rapid and Consistent Induction of Digital Dermatitis in Holstein Calves.

Authors:  Adam C Krull; Vickie L Cooper; John W Coatney; Jan K Shearer; Patrick J Gorden; Paul J Plummer
Journal:  PLoS One       Date:  2016-04-27       Impact factor: 3.240

  3 in total

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