Literature DB >> 15942489

Intralesional injection of Tisseel fibrin glue for resection of lymphangiomas and other thin-walled orbital cysts.

Patrick R Boulos1, Mona Harissi-Dagher, Conrad Kavalec, Isabelle Hardy, François Codère.   

Abstract

PURPOSE: Surgical removal of orbital lymphangiomas is often difficult because the capsule of these lesions is fragile, and, once violated, it tends to collapse, making identification of residual tumor difficult and dissection often incomplete. A surgical technique combining partial controlled decompression of the lesion with intralesional injection of Tisseel fibrin glue is evaluated to determine its effectiveness in resecting the lesion and preventing recurrences.
METHODS: This is a retrospective interventional case series. Three young patients, two with lymphangiomas and one with congenital hydrocystoma, underwent surgical resection of their thin-walled cystic lesions of the orbit with the use of intralesional injection of Tisseel fibrin glue. Resolution of the signs and symptoms, complications of the surgery, and recurrence of bleeding are the parameters studied.
RESULTS: All 3 patients had improvement of their signs and symptoms. None had complications related to the surgery, and no recurrence of bleeding occurred during the follow-up period.
CONCLUSIONS: Our study suggests that this surgical technique with intralesional injection of Tisseel fibrin glue is an effective treatment modality for the resection of lymphangiomas and other orbital thin-walled cystic lesions.

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Year:  2005        PMID: 15942489     DOI: 10.1097/01.iop.0000160594.06829.00

Source DB:  PubMed          Journal:  Ophthalmic Plast Reconstr Surg        ISSN: 0740-9303            Impact factor:   1.746


  8 in total

1.  Lacrimal Gland Intra-Lobular Duct Cysts Associated with Focal Vasculitis.

Authors:  Hardeep Singh Mudhar; Zanna I Currie; Sachin M Salvi
Journal:  Ocul Oncol Pathol       Date:  2015-04-01

Review 2.  Sclerotherapy for Orbital Lymphangioma - Case Series and Literature Review.

Authors:  Karnesh Chandrakant Patel; George Kalantzis; Nabil El-Hindy; Bernard Y Chang
Journal:  In Vivo       Date:  2017 Mar-Apr       Impact factor: 2.155

3.  Interventions for orbital lymphangioma.

Authors:  Sheel R Patel; Jamie B Rosenberg; Anne Barmettler
Journal:  Cochrane Database Syst Rev       Date:  2019-05-15

4.  Clinical Assessment and Lesion-Specific Management of Orbital Vascular Malformations.

Authors:  Daniel B Rootman; Stefania B Diniz; Liza M Cohen
Journal:  J Neurol Surg B Skull Base       Date:  2021-03-23

5.  Intraoperative use of indocyanine green and trypan blue mixed with fibrin glue in the excision of periocular cystic lesions.

Authors:  Nariman S Boyle; Eli L Chang
Journal:  Am J Ophthalmol Case Rep       Date:  2020-11-13

Review 6.  [Sclerotization of orbital lymphangioma with OK-432].

Authors:  W Lagrèze; M Metzger; J Rössler
Journal:  Ophthalmologe       Date:  2014-05       Impact factor: 1.059

7.  Orbital Lymphangioma: Characteristics and Treatment Outcomes of 12 Cases.

Authors:  Young Jun Woo; Chang Yeom Kim; Bradford Sgrignoli; Jin Sook Yoon
Journal:  Korean J Ophthalmol       Date:  2017-05-12

8.  Intralesional injection of OK-432 for vision-threatening orbital lymphangioma.

Authors:  Jin Sook Yoon; Jung Bum Choi; Sung Joo Kim; Sang Yeul Lee
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2007-02-14       Impact factor: 3.535

  8 in total

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