Jennifer L Kuk1, SoJung Lee, Steven B Heymsfield, Robert Ross. 1. School of Physical and Health Education and the Department of Medicine, Division of Endocrinology and Metabolism, Queen's University, Kingston, Canada.
Abstract
BACKGROUND: The influence of age and sex on the distribution of abdominal adipose tissue for a given waist circumference (WC) is unclear. OBJECTIVE: The objective was to investigate the influence of age and sex on total (TAAT), visceral (VAT), and abdominal subcutaneous (ASAT) adipose tissue for a given WC. DESIGN: Body composition was assessed by whole-body magnetic resonance imaging in 147 younger men (< 50 y), 83 older men, 171 younger (premenopausal) women, and 80 older (postmenopausal) women with a wide range (16-40; in kg/m(2)) of body mass indexes. RESULTS: Within each sex, the regression lines between WC and TAAT were not significantly different (P > 0.1) between younger and older groups. Collapsed across age groups, women had more TAAT for a given WC than did men; however, this difference was significantly reduced with increasing WC (P < 0.05). Within each sex, regression lines derived for WC and ASAT were not significantly different between younger and older groups (P > 0.1). Collapsed across age groups, women had 1.8 kg more ASAT for a given WC (P < 0.05) than did men across the range of WCs. Within each sex, older men and women had a significantly greater increase in VAT for a given WC (P < 0.05) than did younger men and women. Furthermore, independent of age group, the slopes for WC and VAT were significantly higher (P < 0.05) in men than in women. CONCLUSIONS: There are significant sex differences in TAAT, VAT, and ASAT for a given WC. Furthermore, the relation between WC and VAT is substantially influenced by age.
BACKGROUND: The influence of age and sex on the distribution of abdominal adipose tissue for a given waist circumference (WC) is unclear. OBJECTIVE: The objective was to investigate the influence of age and sex on total (TAAT), visceral (VAT), and abdominal subcutaneous (ASAT) adipose tissue for a given WC. DESIGN: Body composition was assessed by whole-body magnetic resonance imaging in 147 younger men (< 50 y), 83 older men, 171 younger (premenopausal) women, and 80 older (postmenopausal) women with a wide range (16-40; in kg/m(2)) of body mass indexes. RESULTS: Within each sex, the regression lines between WC and TAAT were not significantly different (P > 0.1) between younger and older groups. Collapsed across age groups, women had more TAAT for a given WC than did men; however, this difference was significantly reduced with increasing WC (P < 0.05). Within each sex, regression lines derived for WC and ASAT were not significantly different between younger and older groups (P > 0.1). Collapsed across age groups, women had 1.8 kg more ASAT for a given WC (P < 0.05) than did men across the range of WCs. Within each sex, older men and women had a significantly greater increase in VAT for a given WC (P < 0.05) than did younger men and women. Furthermore, independent of age group, the slopes for WC and VAT were significantly higher (P < 0.05) in men than in women. CONCLUSIONS: There are significant sex differences in TAAT, VAT, and ASAT for a given WC. Furthermore, the relation between WC and VAT is substantially influenced by age.
Authors: S Bonekamp; P Ghosh; S Crawford; S F Solga; A Horska; F L Brancati; A M Diehl; S Smith; J M Clark Journal: Int J Obes (Lond) Date: 2007-08-14 Impact factor: 5.095
Authors: Vicente Gilsanz; James Chalfant; Ashley O Mo; David C Lee; Frederick J Dorey; Steven D Mittelman Journal: J Clin Endocrinol Metab Date: 2009-06-16 Impact factor: 5.958
Authors: Bram van den Borst; Harry R Gosker; Annemarie Koster; Binbing Yu; Stephen B Kritchevsky; Yongmei Liu; Bernd Meibohm; Thomas B Rice; Michael Shlipak; Sachin Yende; Tamara B Harris; Annemie M W J Schols Journal: Am J Clin Nutr Date: 2012-07-18 Impact factor: 7.045
Authors: Susanne Holzhauer; Renate M L Zwijsen; Vincent W V Jaddoe; Guenther Boehm; Henriette A Moll; Paul G Mulder; Veronica A Kleyburg-Linkers; Albert Hofman; Jacqueline C M Witteman Journal: Eur J Epidemiol Date: 2009-07-29 Impact factor: 8.082