Literature DB >> 15939329

Chemical library synthesis using convergent approaches.

Aaron B Beeler1, Scott E Schaus, John A Porco.   

Abstract

New strategies are continuously being developed in combinatorial and diversity-oriented synthesis. Convergent design in target-oriented synthesis is commonly employed for construction of complex molecules. In this mini-review, we describe examples of convergent library design and synthesis as well as potential areas for future development.

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Year:  2005        PMID： 15939329     DOI： 10.1016/j.cbpa.2005.04.005

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  4 in total

1.  Metallacycle-Mediated Cross-Coupling in Natural Product Synthesis.

Authors:  Natasha F O'Rourke; Matthew J Kier; Glenn C Micalizio
Journal:  Tetrahedron       Date:  2016-09-07       Impact factor: 2.457

2.  Stepwise aromatic nucleophilic substitution in continuous flow. Synthesis of an unsymmetrically substituted 3,5-diamino-benzonitrile library.

Authors:  László Lengyel; Viktor Gyóllai; Tamás Nagy; György Dormán; Péter Terleczky; Viktor Háda; Katalin Nógrádi; Ferenc Sebok; László Urge; Ferenc Darvas
Journal:  Mol Divers       Date:  2010-12-29       Impact factor: 2.943

3.  Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions.

Authors:  Ciaran P Seath; David B Vogt; Zihao Xu; Allyson J Boyington; Nathan T Jui
Journal:  J Am Chem Soc       Date:  2018-11-05       Impact factor: 15.419

Review 4.  Towards the optimal screening collection: a synthesis strategy.

Authors:  Thomas E Nielsen; Stuart L Schreiber
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336
  4 in total

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