| Literature DB >> 15939090 |
Mohamad A Mikati1, Michele P Zeinieh, Rana M Kurdi, Samer A Harb, Jimmy A El Hokayem, Rita H Daderian, Alhan Shamseddine, Makram Obeid, Fadi F Bitar, Marwan El Sabban.
Abstract
Ten-day-old rat pups (P10) subjected to acute hypoxia (down to 4% O2) had as adults increased aggression (handling test), memory impairment (water maze test), and decreased CA1 cell counts. Pups subjected to chronic hypoxia (10% O2 from P0 to P21) had increased aggression, hyperactivity (open-field test), and decreased CA1 cell counts. Chronic hypoxia with superimposed acute hypoxia resulted in consequences that were not different from those of chronic hypoxia.Entities:
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Year: 2005 PMID： 15939090 DOI： 10.1016/j.devbrainres.2005.03.007
Source DB: PubMed Journal: Brain Res Dev Brain Res ISSN： 0165-3806