Literature DB >> 15934050

1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.

Ashraf Brik1, Jerry Alexandratos, Ying-Chuan Lin, John H Elder, Arthur J Olson, Alexander Wlodawer, David S Goodsell, Chi-Huey Wong.   

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Year:  2005        PMID： 15934050     DOI： 10.1002/cbic.200500101

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  45 in total

1.  Click chemistry for targeted protein ubiquitylation and ubiquitin chain formation.

Authors:  Daniel Rösner; Tatjana Schneider; Daniel Schneider; Martin Scheffner; Andreas Marx
Journal:  Nat Protoc       Date:  2015-09-24       Impact factor: 13.491

Review 2.  Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.

Authors:  Arun K Ghosh; Heather L Osswald; Gary Prato
Journal:  J Med Chem       Date:  2016-01-22       Impact factor: 7.446

3.  Asymmetric cross-dehydrogenative coupling enabled by the design and application of chiral triazole-containing phosphoric acids.

Authors:  Andrew J Neel; Jörg P Hehn; Pascal F Tripet; F Dean Toste
Journal:  J Am Chem Soc       Date:  2013-09-11       Impact factor: 15.419

4.  Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models.

Authors:  Melissa J Leyva; Francesco Degiacomo; Linda S Kaltenbach; Jennifer Holcomb; Ningzhe Zhang; Juliette Gafni; Hyunsun Park; Donald C Lo; Guy S Salvesen; Lisa M Ellerby; Jonathan A Ellman
Journal:  Chem Biol       Date:  2010-11-24

5.  Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system.

Authors:  Ying-Chuan Lin; Ashraf Brik; Aymeric de Parseval; Karen Tam; Bruce E Torbett; Chi-Huey Wong; John H Elder
Journal:  J Virol       Date:  2006-08       Impact factor: 5.103

Review 6.  Tetrahydrofuran, tetrahydropyran, triazoles and related heterocyclic derivatives as HIV protease inhibitors.

Authors:  Arun K Ghosh; David D Anderson
Journal:  Future Med Chem       Date:  2011-07       Impact factor: 3.808

7.  Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase.

Authors:  Emelia Awuah; Eric Ma; Annabelle Hoegl; Kenward Vong; Eric Habib; Karine Auclair
Journal:  Bioorg Med Chem       Date:  2014-04-24       Impact factor: 3.641

8.  Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for Chagas disease chemotherapy.

Authors:  Katrien Brak; Iain D Kerr; Kimberly T Barrett; Nobuhiro Fuchi; Moumita Debnath; Kenny Ang; Juan C Engel; James H McKerrow; Patricia S Doyle; Linda S Brinen; Jonathan A Ellman
Journal:  J Med Chem       Date:  2010-02-25       Impact factor: 7.446

Review 9.  Molecular mechanisms of FIV infection.

Authors:  John H Elder; Magnus Sundstrom; Sohela de Rozieres; Aymeric de Parseval; Chris K Grant; Ying-Chuan Lin
Journal:  Vet Immunol Immunopathol       Date:  2008-01-19       Impact factor: 2.046

10.  A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant.

Authors:  Michael J Giffin; Holly Heaslet; Ashraf Brik; Ying-Chuan Lin; Gabrielle Cauvi; Chi-Huey Wong; Duncan E McRee; John H Elder; C David Stout; Bruce E Torbett
Journal:  J Med Chem       Date:  2008-09-30       Impact factor: 7.446
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