Literature DB >> 1593398

Use of polylactic acid for the preparation of microparticulate drug delivery systems.

B Conti1, F Pavanetto, I Genta.   

Abstract

This report reviews the development of particulate drug delivery systems technology based on polylactic acid (PLA). The following methods used to produce PLA microparticles are considered: emulsion solvent evaporation, emulsion solvent extraction, interfacial phase deposition, spray coating, and the melting method. The different preparation processes and parameters used, the characteristics of microparticles obtained and those parameters affecting the characteristics of these systems, are discussed.

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Year:  1992        PMID： 1593398     DOI： 10.3109/02652049109021231

Source DB:  PubMed          Journal:  J Microencapsul        ISSN： 0265-2048            Impact factor:   3.142


  4 in total

1.  Attachment of an aminoglycoside, amikacin, to implantable collagen for local delivery in wounds.

Authors:  S T Boyce; A P Supp; G D Warden; I A Holder
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

2.  Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes.

Authors:  S T Boyce; G D Warden; I A Holder
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

3.  Ocular biocompatibility and structural integrity of micro- and nanostructured poly(caprolactone) films.

Authors:  Daniel A Bernards; Robert B Bhisitkul; Paula Wynn; Mark R Steedman; On-Tat Lee; Fergus Wong; Somanus Thoongsuwan; Tejal A Desai
Journal:  J Ocul Pharmacol Ther       Date:  2013-02-07       Impact factor: 2.671

4.  Optimization of experimental parameters for the production of LMWH-loaded polymeric microspheres.

Authors:  Nusrat Motlekar; Bi-Botti Youan
Journal:  Drug Des Devel Ther       Date:  2009-02-06       Impact factor: 4.162
  4 in total

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