Literature DB >> 15933470

Surgical considerations for management of distal extremity soft tissue sarcomas.

Peter C Ferguson1.   

Abstract

PURPOSE OF REVIEW: This review focuses on the surgical management of soft tissue sarcomas of the hands and the feet. With recent advances in limb salvage surgery and radiotherapy delivery, local control of soft tissue sarcoma in the extremity has become optimized, and the associated functional results of this treatment have taken on extreme importance. Techniques to limit the amount of normal tissue resected and to reconstruct the resulting defects are critical to the final functional result. RECENT
FINDINGS: Several features of soft tissue sarcoma unique to the hand and foot have been reported. Certain histologic subtypes of soft tissue sarcoma have been noted to arise preferentially in the hand and the foot, such as epithelioid sarcoma, clear cell sarcoma, and synovial sarcoma. Patients with hand and foot sarcomas have been described as having improved overall survival, but this is likely a result of the smaller size of tumors arising in these locations. Reconstruction of bone defects using various techniques, vascular reconstruction, tendon transfers, and soft tissue reconstruction using regional flaps in the hand and free flaps in the foot have resulted in good functional outcomes. Amputation and early prosthetic fitting still have a role in management of some soft tissue sarcomas, most frequently in the foot.
SUMMARY: Limb salvage remains the standard of care for extremity soft tissue sarcomas. Given the fact that patients have good oncologic and functional outcomes with limb salvage in tumors in the hand and foot, surgical oncologists should have this goal for each patient.

Entities:  

Mesh:

Year:  2005        PMID: 15933470     DOI: 10.1097/01.cco.0000166651.38417.c8

Source DB:  PubMed          Journal:  Curr Opin Oncol        ISSN: 1040-8746            Impact factor:   3.645


  8 in total

1.  [Surgical margins in soft tissue sarcoma of the extremities].

Authors:  H-U Steinau; L Steinsträsser; S Langer; I Stricker; O Goertz
Journal:  Pathologe       Date:  2011-02       Impact factor: 1.011

2.  A slow-growing prepatellar mass in a 31-year-old woman.

Authors:  J L Bron; W J Mooi; R Saouti; P I J M Wuisman
Journal:  Clin Orthop Relat Res       Date:  2008-02-08       Impact factor: 4.176

3.  Multimodality treatment of locally advanced soft-tissue sarcomas of the extremities.

Authors:  Vincenzo Ravo; Immacolata Marrone; Anna Morra; Roberto Manzo; Paola Murino; Fabrizio Cammarota; Paolo Muto
Journal:  Rep Pract Oncol Radiother       Date:  2010-10-06

4.  MR imaging appearances of soft tissue flaps following reconstructive surgery of the lower extremity.

Authors:  Olaf Magerkurth; Gandikota Girish; Jon A Jacobson; Sung Moon Kim; Monica K Brigido; Qian Dong; David A Jamadar
Journal:  Korean J Radiol       Date:  2015-01-09       Impact factor: 3.500

5.  Amputation risk after the revascularization procedures in sarcoma resections.

Authors:  Luiz Eduardo Moreira Teixeira; Thiago Marques Leão; Daniel Barbosa Regazzi; Cláudio Beling Gonçalves Soares
Journal:  Rev Bras Ortop       Date:  2017-10-21

6.  Free Gracilis Muscle Flap for Sarcoma Reconstruction: 19 Years of Clinical Experience.

Authors:  Rachel Pedreira; Nicholas A Calotta; E Gene Deune
Journal:  Sarcoma       Date:  2019-02-03

7.  The pathologic response of resected synovial sarcomas to hyperthermic isolated limb perfusion with melphalan and TNF-α: a comparison with the whole group of resected soft tissue sarcomas.

Authors:  Benjamin Schwindenhammer; Lars Erik Podleska; Andrea Kutritz; Sebastian Bauer; Sien-Yi Sheu; Georg Taeger; Kurt Werner Schmid; Florian Grabellus
Journal:  World J Surg Oncol       Date:  2013-08-12       Impact factor: 2.754

8.  Clinical outcomes for patients with synovial sarcoma of the hand.

Authors:  Hidetatsu Outani; Kenichiro Hamada; Kazuya Oshima; Susumu Joyama; Norifumi Naka; Nobuhito Araki; Takafumi Ueda; Hideki Yoshikawa
Journal:  Springerplus       Date:  2014-11-03
  8 in total

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