| Literature DB >> 15932220 |
Eric L Elliott1, Simon M Bushell, Marta Cavero, Brian Tolan, T Ross Kelly.
Abstract
[reaction: see text] The first syntheses of the pyridazinoindazolium alkaloids nigellicine and nigeglanine hydrobromide via a common intermediate are described. Ortho-lithiation/acylation and the direct amination of an isatin ring system are the key steps in the synthesis.Entities:
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Year: 2005 PMID： 15932220 DOI： 10.1021/ol050769m
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005